Methotrexate, Sensitive

2005405
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Ordering Recommendation

Monitor methotrexate concentration.

Mnemonic

METREXSN

Methodology

Quantitative Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain Red. Also acceptable: Green (Sodium or Lithium Heparin), Lavender (EDTA), or Pink (K2EDTA).

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Serum separator tubes.

Remarks
Stability

After separation from cells: Ambient: 4 hours; Refrigerated: 2 weeks; Frozen: 6 months

Reference Interval

Effective August 15, 2011

Therapeutic Range
Low dose 0.50-1.00 µmol/L
High dose/24 hours 5.00 µmol/L or less
48 hours 0.50 µmol/L or less
72 hours 0.10 µmol/L or less

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

80204

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Components

Component Test Code* Component Chart Name LOINC
2005406 Methotrexate, Sensitive 14836-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • methotrexate concentration
  • methotrexate drug level
  • MTX
Methotrexate, Sensitive