Ordering Recommendation
Monitor methotrexate concentration.
Mnemonic
METREXSN
Methodology
Quantitative Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Plain Red. Also acceptable: Green (Sodium or Lithium Heparin), Lavender (EDTA), or Pink (K2EDTA).
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3 mL serum to an ARUP Transport Tube. (Min: 1 mL)
Storage/Transport Temperature
Frozen.
Unacceptable Conditions
Serum separator tubes.
Remarks
Stability
After separation from cells: Ambient: 4 hours; Refrigerated: 2 weeks; Frozen: 6 months
Reference Interval
Effective August 15, 2011
Therapeutic Range |
|
---|---|
Low dose | 0.50-1.00 µmol/L |
High dose/24 hours | 5.00 µmol/L or less |
48 hours | 0.50 µmol/L or less |
72 hours | 0.10 µmol/L or less |
Interpretive Data
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
80204
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2005406 | Methotrexate, Sensitive | 14836-1 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- methotrexate concentration
- methotrexate drug level
- MTX
Methotrexate, Sensitive