2005373
print

Alternative Complement Pathway Activity (AH50)

AH50
Example Reports
Abnormal
Normal

Ordering Recommendation

Initial screening for suspected deficiency in the alternative complement pathway.

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay (ELISA)

Performed

Sun, Wed

Reported

7-14 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain Red

Specimen Preparation

Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP and centrifuge at 2-8 degrees C and aliquot serum into ARUP standard transport tube. Freeze specimen immediately at -70 degrees C or lower freezer. (Min: 0.3 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Specimen types other than serum collected from RED TOP tubes. SST or serum gel tubes are not acceptable. Refrigerated or room temperature specimens. Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles. Grossly hemolyzed or grossly lipemic specimens or icteric specimens.

Remarks
Stability

After separation from cells: Ambient: unacceptable; Refrigerated: Unacceptable; Frozen: 30 days if kept at -70 C

Reference Interval

Test Number
 Components
 Reference Interval
  Alternative Complement Pathway Activity 31 percent normal or greater

Interpretive Data

See report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/21/2023
X
X
X
X
X
X
X
N/A

CPT Codes

86161

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
2005374 Alternative Complement Pathway Activity 74520-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • AH50
  • Alternate Pathway
  • atypical hemolytic uremic syndrome
  • C3 glomerulonephrits
  • Dense-deposit disease
  • Functional Complement
  • Hemolytic Complement
Alternative Complement Pathway Activity (AH50)