2005287
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Chromatin Antibody, IgG

CHROMATIN
Example Reports
Negative
Positive

Ordering Recommendation

Aids in the diagnosis of systemic lupus erythematosus (SLE).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Urine or plasma. Contaminated, heat-inactivated, severely hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon, Wed, Fri

Reported

1-4 days

Reference Interval

19 Units or less Negative
20-60 Units Moderate Positive
61 Units or greater Strong Positive

Interpretive Data

The presence of anti-chromatin antibodies may be useful in the diagnosis of systemic lupus erythematosus (SLE) or drug-induced lupus (DIL) and have been reported to be predictive of lupus nephritis, especially when antibody levels are high.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

83516

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Components

Component Test Code* Component Chart Name LOINC
2005288 Chromatin Antibody, IgG 32580-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Anti-Chromatin
  • Anti-DNP
  • Anti-Nucleosome
  • Antichromatin
  • Antinucleosome
  • Chromatin Antibodies
  • chromatin IgG Ab
  • H2A-H2B-H3-H4
  • LE-Cell Factor
  • Nucleosome
Chromatin Antibody, IgG