Connect Sign In
Chromatin Antibody, IgG
Ordering Recommendation
Aids in the diagnosis of systemic lupus erythematosus (SLE).
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Refrigerated.
Urine or plasma. Contaminated, heat-inactivated, severely hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Wed, Fri
Reported
1-4 days
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| Chromatin Antibody, IgG | 19 Units or less |
Interpretive Data
The presence of anti-chromatin antibodies may be useful in the diagnosis of systemic lupus erythematosus (SLE) or drug-induced lupus (DIL) and have been reported to be predictive of lupus nephritis, especially when antibody levels are high.
| Component |
Interpretation |
|---|---|
| Chromatin Antibody, IgG | 19 Units or less Negative 20-60 Units Moderate Positive 61 Units Strong Positive |
FDA
Note
Hotline History
CPT Codes
83516
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2005288 | Chromatin Antibody, IgG | 32580-3 |
Aliases
- Nucleosome
- H2A-H2B-H3-H4
- LE-Cell Factor
- Anti-Chromatin
- Anti-DNP
- Anti-Nucleosome
- Antichromatin
- Antinucleosome
- Chromatin Antibodies
- chromatin IgG Ab
