Ordering Recommendation

This test is used to evaluate and monitor methylmalonic acidemia.

Mnemonic
MMA METD
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red or serum separator tube. Also acceptable: Green (sodium or lithium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation

Centrifuge and remove serum or plasma from cells within 2 hours of collection. Immediately transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and
refrigerate or freeze. (Min: 1 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Room temperature specimens. Grossly hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month

Reference Interval

Effective July 18, 2011

0.00-0.40 µmol/L

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

83921

Components
Component Test Code* Component Chart Name LOINC
2005256 MMA Serum/Plasma, Metabolic Disorder 13964-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • MMA (Methylmalonic Acid, Serum or Plasma (Metabolic Disorders))
Methylmalonic Acid, Serum or Plasma (Metabolic Disorders)