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Bilirubin, CSF
Ordering Recommendation
Useful as an indicator of in vivo breakdown of hemoglobin to differentiate cerebral hemorrhage from a traumatic tap.
New York DOH Approval Status
Specimen Required
CSF. Collect at least 12 hours after suspected hemorrhage. Use the last (ideally the fourth) specimen post lumbar puncture. AND serum separator tube.
CSF: Transport to local lab quickly and avoid pneumatic tube transport if possible. Protect from light during collection, storage, and shipment. Centrifuge for 5 minutes ASAP or within 1 hour of collection. Transfer 2 mL CSF to an ARUP amber transport tube. (Min: 1 mL) Do not freeze.
Serum: Protect from light during collection, storage and shipment. Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP amber transport tube. (Min: 0.5 mL)
Refrigerated.
Specimens not protected from light. Frozen CSF.
CSF: Ambient: 4 hours; Refrigerated: 1 week; Frozen: Unacceptable
Serum: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months
Methodology
Quantitative Spectrophotometry
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| Net Absorbance, Bilirubin, CSF | 0.007 AU or less | |
| Net Absorbance, Oxyhemoglobin, CSF | 0.020 AU or less | |
| Serum Bilirubin | Refer to Report |
Interpretive Data
Refer to report.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
84311 x2; 82247
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2005249 | Net Absorbance, Bilirubin, CSF | |
| 2005250 | Net Absorbance, Oxyhemoglobin, CSF | |
| 2005252 | Serum Bilirubin | 1975-2 |
Aliases
- Total bilirubin
- Xanthochromia
- Bilirubin, Total, Body Fluid
- TBILI-FL
- TBIL
- TBILI
- BILIT
- Bili Total BF
