Ordering Recommendation

Useful as an indicator of in vivo breakdown of hemoglobin to differentiate cerebral hemorrhage from a traumatic tap.

Mnemonic
BILCSF
Methodology

Quantitative Spectrophotometry

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

CSF. Collect at least 12 hours after suspected hemorrhage. Use the last (ideally the fourth) specimen post lumbar puncture. AND serum separator tube.

Specimen Preparation

CSF: Transport to local lab quickly and avoid pneumatic tube transport if possible. Protect from light during collection, storage and shipment. Centrifuge for 5 minutes ASAP or within 1 hour of collection. Transfer 2 mL CSF to an ARUP Amber Transport Tube. (Min: 1 mL) Do not freeze.
Serum: Protect from light during collection, storage and shipment. Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Amber Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Specimens not protected from light. Frozen CSF.

Remarks
Stability

CSF: Ambient: 4 hours; Refrigerated: 1 week; Frozen: Unacceptable
Serum: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 6 months

Reference Interval

Effective July 18, 2011

Test Number
Components
Reference Interval
  Net Absorbance, Bilirubin, CSF Effective July 18, 2011
0.007 AU or less
  Net Absorbance, Oxyhemoglobin, CSF Effective July 18, 2011
0.020 AU or less
0020032 Bilirubin, Total, Serum or Plasma By report

Interpretive Data

Refer to report.

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

84311 x2; 82247

Components
Component Test Code* Component Chart Name LOINC
2005249 Net Absorbance, Bilirubin, CSF
2005250 Net Absorbance, Oxyhemoglobin, CSF
2005252 Serum Bilirubin 1975-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Xanthochromia
Bilirubin, CSF