Determine antiviral drug resistance to cidofovir, foscarnet sodium, and ganciclovir.
Polymerase Chain Reaction/Sequencing
Lavender (EDTA), pink (K2EDTA) or plasma preparation tube.
Separate plasma from cells within 8 hours. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)
Please submit most recent viral load and test date, if available.
Ambient: 8 hours; Refrigerated: 72 hours; Frozen: 1 month
Codons 457-630 of the UL97 gene and codons 393-1000 of the UL54 gene are sequenced. Mutations associated with resistance to ganciclovir, cidofovir, and foscarnet are reported. Mutations in viral sub-populations below 20 percent of total may not be detected.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
This test may be unsuccessful if the plasma CMV DNA viral load is less than 1,500 CMV DNA copies per mL of plasma.
|Component Test Code*||Component Chart Name||LOINC|
|2004761||CMV Cidofovir Resistance||72856-8|
|2004762||CMV Foscarnet Resistance||42317-8|
|2004763||CMV Ganciclovir Resistance||72854-3|
- CMV Genotype
- CMV Genotyping
- CMV Resistance
- CMV Resistance Genotype
- CMV Resistance Sequencing
- CMV Sequencing
- CMV UL54
- CMV UL54 Genotype
- CMV UL97
- CMV UL97 Genotype
- CMV UL97/UL54 Genotype
- Cytomegalovirus Resistance