Ordering Recommendation

Mnemonic

MACROAMY

Methodology

Quantitative Ultrafiltration/Quantitative Enzymatic

Performed

Thu

Reported

2-9 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plasma separator tube, serum separator tube, or plain red.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 2 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1.1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Specimens containing calcium chelating anticoagulants such as citrates, EDTA, or oxalates.

Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month

Reference Interval

Test Number
Components
Reference Interval
  Amylase, Total
3-90 days 0-30 U/L
3-6 months 7-40 U/L
7-8 months 7-57 U/L
9-11 months 11-70 U/L
12-17 months 11-79 U/L
18-35 months 19-92 U/L
3-4 years 26-106 U/L
5-12 years 30-119 U/L
13 years and older 30-110 U/L

  Amylase, Monomeric
18 years and older 23-110 U/L

  Amylase, Percent Monomeric Greater than or equal to 71 percent

Interpretive Data

An amylase, monomeric result above the upper reference limit is consistent with hyperamylasemia. An amylase, percent monomeric less than 71 percent suggests the presence of macroamylase.

Amylase, monomeric is determined after ultrafiltration. Macroamylase is removed by ultrafiltration and is not measured.

For confirmation of macroamylasemia, consider ordering Amylase, Urine (ARUP test code 0020471).

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

82150; 84999

Components

Component Test Code* Component Chart Name LOINC
2004465 Amylase, Total 1798-8
2004466 Amylase, Monomeric 2591-6
2004467 Amylase, Percent Monomeric 26011-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Monomeric Amylase
  • monomeric and total amylase
  • serum macroamylase
Macroamylase Determination