Aids in the diagnosis of type I and II leukocyte adhesion deficiency. Panel measures CD11a, CD11b, CD15s, and CD18 on neutrophils.
Semi-Quantitative Flow Cytometry
New York DOH Approval Status
Green (Na-Heparin) or Purple (K-EDTA)..
Transport 5 mL whole blood. (Min: 1 mL) Specimen must be analyzed within 72 hours of collection.
Room temperature or refrigerated.
Clotted or hemolyzed specimens. Frozen specimens.
Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable.
Effective November 15, 2021
The Leukocyte Adhesion Deficiency Panel measures the receptors CD11a, CD11b, CD15s, and CD18 normally found on neutrophils. The percentage of patient neutrophils bearing these receptors is reported. Decreased values outside of the reference interval may correlate with abnormal neutrophil function. For example, CD11 and CD18 are decreased or absent in leukocyte adhesion deficiency (LAD) type I and CD15s is decreased or absent in LAD type II.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
- Beta 2 integrins
- CD11a, CD11b; CD15s; CD18
- LAD I, II determination