Chat
Leukocyte Adhesion Deficiency Panel
Copy Utility
Ordering Recommendation
Aids in the diagnosis of type I and II leukocyte adhesion deficiency. Panel measures CD11b, CD15, and CD18 on neutrophils.
Mnemonic
Methodology
Semi-Quantitative Flow Cytometry
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
Specimen Required
Green (Sodium or Lithium Heparin).
Transport 5 mL whole blood. (Min: 1 mL) Specimen must be analyzed within 48 hours of collection.
Refrigerated.
Clotted or hemolyzed specimens.
Ambient: Unacceptable; Refrigerated: 48 hours; Frozen: Unacceptable
Reference Interval
Effective August 20, 2012
| Available Separately |
Component |
Reference Interval |
|---|---|---|
| No | % CD11b | 93-100% |
| No | % CD15 | 91-100% |
| No | % CD18 | 98-100% |
Interpretive Data
The Leukocyte Adhesion Deficiency Panel measures the receptors CD11b, CD15, and CD18 on neutrophils. The percentage of patient neutrophils bearing these receptors is reported. Although these receptors are normally found on neutrophils; values outside of the reference interval may correlate with abnormal neutrophil function. For example, CD18 is decreased or absent in Leukocyte Adhesion Deficiency (LAD) type I and CD15 is decreased or absent in LAD type II.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
86356 x3
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0095818 | % CD18 | 38170-7 |
| 0095922 | % CD11b | 17110-8 |
| 0095957 | % CD15 | 20590-6 |
Aliases
- Beta 2 integrins
- CD11b; CD15; CD18
- LAD I, II determination
Feedback
