Time Sensitive

Ordering Recommendation

Aids in the diagnosis of type I and II leukocyte adhesion deficiency. Panel measures CD11a, CD11b, CD15s, and CD18 on neutrophils.

New York DOH Approval Status

This test is not New York state approved. Due to short specimen stability it is recommended that this testing be submitted directly to a New York state-approved laboratory. Do not submit sample to ARUP.

Specimen Required

Patient Preparation

Green (Na heparin) or purple (KEDTA).

Specimen Preparation

Transport 5 mL whole blood. (Min: 1 mL) Specimen must be analyzed within 72 hours of collection.

Storage/Transport Temperature

Room temperature or refrigerated.

Unacceptable Conditions

Clotted or hemolyzed specimens. Frozen specimens.


Ambient: 72 hours; Refrigerated: 72 hours; Frozen: Unacceptable.


Semi-Quantitative Flow Cytometry




1-3 days

Reference Interval

Test Number
Reference Interval
  % CD18 99-100
  % CD11b 96-100
  % CD15s 95-100
  % CD11a 97-100

Interpretive Data

The Leukocyte Adhesion Deficiency Panel measures the receptors CD11a, CD11b, CD15s, and CD18 normally found on neutrophils. The percentage of patient neutrophils bearing these receptors is reported. Decreased values outside of the reference interval may correlate with abnormal neutrophil function. For example, CD11 and CD18 are decreased or absent in leukocyte adhesion deficiency (LAD) type I and CD15s is decreased or absent in LAD type II.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

86356 x4


Component Test Code* Component Chart Name LOINC
0095818 % CD18 17121-5
0095922 % CD11b 17110-8
0095957 % CD15s 17117-3
3004266 % CD11a 17109-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Beta 2 integrins
  • CD11a, CD11b; CD15s; CD18
  • LAD I, II determination
Leukocyte Adhesion Deficiency Panel