Ordering Recommendation

Preferred first-tier test for developmental delay, multiple anomalies, and autism-spectrum disorders. Testing is performed on peripheral blood.

Mnemonic

CMA SNP

Methodology

Genomic Microarray (Oligo-SNP Array)

Performed

Sun-Sat

Reported

10-14 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation
Collect

Collect: Green (Sodium Heparin). Peripheral blood required. Also acceptable: Lavender (K2EDTA).
New York State Clients: Green (Sodium Heparin) AND Lavender (K2EDTA).

Specimen Preparation

Transport 5 mL whole blood. (Min: 1 mL)
New York State Clients: Transport 4 mL whole blood in the original Green (Sodium Heparin) tube and 3 mL whole blood in the original Lavender (K2EDTA) tube. (Min: 2 mL Sodium Heparin and 2 mL EDTA).

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Clotted specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 72 hours; Frozen: Unacceptable
New York State Clients: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

Interpretive Data

Refer to report.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)

Note

This test must be ordered using a Cytogenetic test request form 43097 or through your ARUP interface. Please submit the Genomic Microarray Patient Clinical Information Form with the electronic packing list (https://ltd.aruplab.com/Tests/Pdf/76).

Hotline History

N/A

CPT Codes

81229

Components

Component Test Code* Component Chart Name LOINC
2003415 Cytogenomic SNP Microarray 62375-1
2003416 EER Cytogenomic SNP Microarray 11526-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • aCGH
  • Array CGH
  • Array Comparative Genomic Hybridization
  • CGH
  • Chromosomal Microarray
  • CMA
  • Comparative Genomic Hybridization
  • Congenital Array
  • Constitutional Array
  • Genomic Microarray
  • Microarray
  • Molecular Karyotype
  • Oligo Array
  • Oligonucleotide Array
  • Single-nucleotide-polymorphism (SNP) array
  • Targeted Array
  • Whole Genome Array
Cytogenomic SNP Microarray