Ordering Recommendation
Mnemonic
CORT TMS
Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Wed, Sat

Reported

2-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Specimen should be collected between 8-10 a.m.

Collect

Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions
Remarks
Stability

After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 6 months

Reference Interval
Adult Reference Ranges for Cortisol, Serum, µg/dL
AM 4.6-20.6 µg/dL
PM 1.8-13.6 µg/dL
Stimulation 30-60  Minutes Post 0.25 mg Cosyntropin IV Greater than 20.0 µg/dL

Pediatric Reference Ranges for Cortisol, Serum, µg/dL
AM
1-12 months 4.6-23.0 µg/dL
1-5 years 6.0-25.0 µg/dL
6-17 years 4.6-15.0 µg/dL
Stimulation 30-60 Minutes Post 0.25 mg Cosyntropin IV
1-12 months 32.0-60.0 µg/dL
1-5 years 22.0-40.0 µg/dL
6-17 years 17.0-28.0 µg/dL

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

82533

Components
Component Test Code* Component Chart Name LOINC
2003251 Cortisol by LC-MS/MS, Serum or Plasma 2143-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Cortisol by LC-MS/MS, Serum or Plasma