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Cortisol by LC-MS/MS, Serum or Plasma
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Ordering Recommendation
Mnemonic
Methodology
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Performed
Wed, Sat
Reported
2-5 days
New York DOH Approval Status
Specimen Required
Specimen should be collected between 8-10 a.m.
Serum separator tube, lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).
Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Frozen.
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: 6 months
Reference Interval
| Adult Reference Ranges for Cortisol, Serum, µg/dL | |
|---|---|
| AM | 4.6-20.6 µg/dL |
| PM | 1.8-13.6 µg/dL |
| Stimulation 30-60 Minutes Post 0.25 mg Cosyntropin IV | Greater than 20.0 µg/dL |
| Pediatric Reference Ranges for Cortisol, Serum, µg/dL | |
|---|---|
| AM | |
| 1-12 months | 4.6-23.0 µg/dL |
| 1-5 years | 6.0-25.0 µg/dL |
| 6-17 years | 4.6-15.0 µg/dL |
| Stimulation 30-60 Minutes Post 0.25 mg Cosyntropin IV | |
| 1-12 months | 32.0-60.0 µg/dL |
| 1-5 years | 22.0-40.0 µg/dL |
| 6-17 years | 17.0-28.0 µg/dL |
Interpretive Data
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
CPT Codes
82533
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2003251 | Cortisol by LC-MS/MS, Serum or Plasma | 2143-6 |
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