Optimize drug therapy and monitor patient adherence.
High Performance Liquid Chromatography/Tandem Mass Spectrometry
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated: Also acceptable: Room temperature or frozen.
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Ambient: 15 days; Refrigerated: 15 days; Frozen: 15 days
Effective February 19, 2013
|Therapeutic Range:||Not well established. Suggested range 5.0-10.0 µg/mL|
|Dose-related range (values at doses of 200-600 mg/day):||2.5-18.0 µg/mL|
|Toxic Level||Not well established.|
Adverse effects may include dizziness, fatigue, nausea, vomiting, blurred vision and tremor.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2003183||Lacosamide, Serum or Plasma||59297-2|
- Lacosaminde blood level
- vimpat blood level