Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
LACOSA SP
Methodology

High Performance Liquid Chromatography/Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated: Also acceptable: Room temperature or frozen.

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Remarks
Stability

Ambient: 15 days; Refrigerated: 15 days; Frozen: 15 days

Reference Interval

Effective February 19, 2013

Reference Interval:
Therapeutic Range: Not well established. Suggested range 5.0-10.0 µg/mL
Dose-related range (values at doses of 200-600 mg/day): 2.5-18.0 µg/mL
Toxic Level Not well established.

Interpretive Data

Adverse effects may include dizziness, fatigue, nausea, vomiting, blurred vision and tremor.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

80235

Components
Component Test Code* Component Chart Name LOINC
2003183 Lacosamide, Serum or Plasma 59297-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lacosaminde blood level
  • Vimpat
  • vimpat blood level
Lacosamide, Serum or Plasma