Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
LACOSA SP
Methodology

High Performance Liquid Chromatography/Tandem Mass Spectrometry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated: Also acceptable: Room temperature or frozen.

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Remarks
Stability

Ambient: 15 days; Refrigerated: 15 days; Frozen: 15 days

Reference Interval

Effective February 19, 2013

Reference Interval:
Therapeutic Range: Not well established. Suggested range 5.0-10.0 µg/mL
Dose-related range (values at doses of 200-600 mg/day): 2.5-18.0 µg/mL
Toxic Level Not well established.

Interpretive Data

Adverse effects may include dizziness, fatigue, nausea, vomiting, blurred vision and tremor.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

80235

Components
Component Test Code* Component Chart Name LOINC
2003183 Lacosamide, Serum or Plasma 59297-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lacosaminde blood level
  • Vimpat
  • vimpat blood level
Lacosamide, Serum or Plasma