Optimize drug therapy and monitor patient adherence.
High Performance Liquid Chromatography/Tandem Mass Spectrometry
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated: Also acceptable: Room temperature or frozen.
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Ambient: 15 days; Refrigerated: 15 days; Frozen: 15 days
Effective February 19, 2013
|Therapeutic Range:||Not well established. Suggested range 5.0-10.0 µg/mL|
|Dose-related range (values at doses of 200-600 mg/day):||2.5-18.0 µg/mL|
|Toxic Level||Not well established.|
Adverse effects may include dizziness, fatigue, nausea, vomiting, blurred vision and tremor.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2003183||Lacosamide, Serum or Plasma||59297-2|
- Lacosaminde blood level
- vimpat blood level