Ordering Recommendation
Preferred test to follow-up presumptive results. For general screening, Tapentadol Urine Screen with Reflex to Quantitation (2012294) is preferred.
Mnemonic
Methodology
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed
Mon
Reported
1-8 days
New York DOH Approval Status
Specimen Required
Random urine.
Transfer 2 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)
Refrigerated.
Specimens exposed to repeated freeze/thaw cycles.
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years.
Reference Interval
Effective August 17, 2015
Drugs Covered | Cutoff Concentrations |
Tapentadol | 50 ng/mL |
Tapentadol glucuronide | 100 ng/mL |
Tapentadol-O-sulfate (qualitative only) | 100 ng/mL |
N-desmethyltapentadol (qualitative only) | 100 ng/mL |
Interpretive Data
Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Positive Cutoff:
Tapentadol: 50 ng/mL
Tapentadol glucuronide: 100 ng/mL
Tapentadol-O-sulfate: 100 ng/mL
N-desmethyltapentadol: 100 ng/mL
For medical purposes only; not valid for forensic use.
The presence of metabolite(s) without parent drug is not uncommon and may indicate use over the prior week.
The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
80372 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2003129 | Tapentadol, Urn, Quant | 65807-0 |
2003130 | N-desmethyltapentadol, Urn, Qual | 89306-5 |
2005875 | Tapentadol glucuronide, Urn, Quant | 75362-4 |
2005879 | Tapentadol-O-sulfate, Urn, Qual |
Aliases
- Nucynta
- Tapentadol, Quantitative, Urine
- urine tapentadol concentration