Preferred test to follow-up presumptive results. For general screening, Tapentadol Urine Screen with Reflex to Quantitation (2012294) is preferred.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Sun, Wed, Fri
Transfer 2 mL urine with no additives or preservatives to an ARUP Standard Transport Tube. (Min: 1 mL)
Specimens exposed to repeated freeze/thaw cycles.
Ambient: 1 week; Refrigerated: 1 month; Frozen: 3 years.
Effective August 17, 2015
|Drugs Covered||Cutoff Concentrations|
|Tapentadol glucuronide||100 ng/mL|
|Tapentadol-O-sulfate (qualitative only)||100 ng/mL|
|N-desmethyltapentadol (qualitative only)||100 ng/mL|
Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Tapentadol: 50 ng/mL
Tapentadol glucuronide: 100 ng/mL
Tapentadol-O-sulfate: 100 ng/mL
N-desmethyltapentadol: 100 ng/mL
For medical purposes only; not valid for forensic use.
The presence of metabolite(s) without parent drug is not uncommon and may indicate use over the prior week.
The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, diluted/adulterated urine, or limitations of testing. The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.
Laboratory Developed Test (LDT)
80372 (Alt code: G0480)
|Component Test Code*||Component Chart Name||LOINC|
|2003129||Tapentadol, Urn, Quant||65807-0|
|2003130||N-desmethyltapentadol, Urn, Qual||89306-5|
|2005875||Tapentadol glucuronide, Urn, Quant||75362-4|
|2005879||Tapentadol-O-sulfate, Urn, Qual|
- Tapentadol, Quantitative, Urine
- urine tapentadol concentration