Quetiapine, Serum or Plasma
Ordering Recommendation
Optimize drug therapy and monitor patient adherence.
Methodology
Liquid Chromatography-Tandem Mass Spectrometry
Performed
Wed
Reported
1-8 days
New York DOH Approval Status
Specimen Required
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Refrigerated.
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 4 months
Reference Interval
Effective Date: November 14, 2022
Therapeutic Range: | 100-1000 ng/mL |
Toxic: | Greater than 1000 ng/mL |
Interpretive Data
Quetiapine is an antipsychotic drug indicated for the treatment of schizophrenia and bipolar disorder. The pharmacokinetics of quetiapine are influenced by drug-drug interactions that may inhibit or induce CYP3A4 metabolism. Adverse effects may include somnolence, hypotension, dizziness, fatigue, constipation, weight gain.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
80342 (Alt code: G0480)
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2003119 | Quetiapine, Serum/Plasma | 26776-5 |
Aliases
- (Seroquel®)
- quetiapine blood level
- seroquel
- seroquel blood level