Quetiapine, Serum or Plasma

2003118
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Therapeutic
Toxic

Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic

QUETIAP

Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Wed

Reported

1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Remarks
Stability

Ambient: 1 week; Refrigerated: 1 month; Frozen: 1 month

Reference Interval

Interpretive Data

The following therapeutic ranges and toxic values have been suggested but have not been validated.
Adverse effects may include somnolence, dizziness, fatigue, constipation, weight gain.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Predose Draw (Trough) - Preferred
Therapeutic range 70-170 ng/mL
Toxic: Greater than 1000 ng/mL

Peak Draw (1.5 hour post dose) - Not recommended
Therapeutic range 100-1000 ng/mL
Toxic: Greater than 1500  ng/mL

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

80342 (Alt code: G0480)

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Components

Component Test Code* Component Chart Name LOINC
2003119 Quetiapine, Serum/Plasma 26776-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • (Seroquel®)
  • quetiapine blood level
  • seroquel
  • seroquel blood level
Quetiapine, Serum or Plasma