Ordering Recommendation

Optimize drug therapy and monitor patient adherence.


Liquid Chromatography-Tandem Mass Spectrometry




1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).


Ambient: 24 hours; Refrigerated: 2 weeks; Frozen: 4 months

Reference Interval

Effective Date: November 14, 2022

Therapeutic Range: 100-1000 ng/mL
Toxic: Greater than 1000 ng/mL

Interpretive Data

Quetiapine is an antipsychotic drug indicated for the treatment of schizophrenia and bipolar disorder. The pharmacokinetics of quetiapine are influenced by drug-drug interactions that may inhibit or induce CYP3A4 metabolism. Adverse effects may include somnolence, hypotension, dizziness, fatigue, constipation, weight gain.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

80342 (Alt code: G0480)


Component Test Code* Component Chart Name LOINC
2003119 Quetiapine, Serum/Plasma 26776-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • (Seroquel®)
  • quetiapine blood level
  • seroquel
  • seroquel blood level
Quetiapine, Serum or Plasma