Ordering Recommendation

Aid in detection of prostate cancer in men age 50 and older when used in conjunction with a digital rectal exam. May also be used as an aid to manage and monitor prostate cancer patients.

Mnemonic
PSA COMP
Methodology

Chemiluminescent Immunoassay

Performed

Sun

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain red or serum separator tube.

Specimen Preparation

Transfer 1.0 mL serum to an ARUP standard transport tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed specimens. Any specimens other than serum.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 1 week; Frozen: 1 month

Reference Interval

0 - 3.6 ng/mL

Interpretive Data

This test uses the Siemens' ADVIA Centaur cPSA methodology, which is FDA approved for use as an aid in the detection of prostate cancer in men age 50 and older when used in conjunction with a digital rectal exam. This methodology is also approved as an aid in the management/monitoring of prostate cancer patients. Results obtained with different assay methods or kits cannot be used interchangeably. Prostatic biopsy is required for the diagnosis of cancer. cPSA is generally not elevated in healthy men or with non-prostatic carcinoma. cPSA concentrations may be elevated in benign prostatic hyperplasia or inflammatory conditions of the prostate. Prostate cancer patients under treatment with antiandrogens and LHRH agonists and antagonists may exhibit markedly reduced levels of cPSA. Care should be taken when interpreting values from these individuals.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

84152

Components
Component Test Code* Component Chart Name LOINC
2002931 PSA Complexed 33667-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Complexed PSA
  • cPSA
Prostate Specific Antigen, Complexed