Ordering Recommendation

Detect Epstein-Barr virus in paraffin. Includes interpretation.

Mnemonic
EBV ISH
Methodology

In situ hybridization (ISH)

Performed

Mon-Fri

Reported

2-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Tissue.

Specimen Preparation

Formalin fix (10% neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 5 unstained 5 micron slides. (Min: 4 slides) Protect paraffin block and/or slides from excessive heat.

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5).

Remarks

Include surgical pathology report.

Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval

Negative

Interpretive Data

Refer to report

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Note
Hotline History
N/A
CPT Codes

88365

Components
Component Test Code* Component Chart Name LOINC
2002901 EBV ISH Comment
2002999 ISH Tissue Source 31208-2
2003000 ISH Reference Number 30896-5
2003001 H and E Slide Description 19772-3
2003004 Epstein-Barr Virus (EBV) ISH Result
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EBER ISH
  • EBV by ISH
  • EBV ISH
Epstein-Barr Virus (EBV) by in situ Hybridization, Paraffin (INACTIVE as of 11/16/20: Refer to 3003016 in the November Hotline)