Quantify kappa and lambda light chains in paraffin. Includes interpretation.
In situ hybridization (ISH)
Formalin fix (10% neutral buffered formalin) and paraffin-embed tissue. Transport tissue block or 10 unstained 5 micron slides in a tissue transport kit (ARUP supply #47808). Available online through eSupply using ARUP ConnectTM or contact ARUP Client Services at (800) 522-2787. (Min: 5 slides) Protect paraffin block and/or slides from excessive heat.
Room temperature or refrigerated. Ship in cooled container during summer months.
Specimens fixed or processed in alternative fixatives (alcohol, Prefer®) or heavy metal fixatives (B-4 or B-5). Frozen specimens.
Include surgical pathology report.
Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
|Available Separately||Test Name||Reference Interval|
|No||Kappa by in situ Hybridization, Paraffin||By report|
|No||Lambda by in situ Hybridization, Paraffin||By report|
Refer to report.
Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.
|Component Test Code*||Component Chart Name||LOINC|
|2002887||Kappa/Lambda ISH Comment|
|2002999||ISH Tissue Source||31208-2|
|2003000||ISH Reference Number||30896-5|
|2003001||H and E Slide Description||19772-3|
|2003218||Kappa/Lambda ISH Clonality|
|2003219||Kappa/Lambda ISH Ratio|
- K/L ISH
- Kappa and Lambda ISH
- Kappa and Lambda mRNA Probes