Aids in the diagnosis and monitoring of monoclonal gammopathies. Panel includes serum free light chain testing, eliminating the need for urine monoclonal studies as part of initial screening. Use to detect, quantify, and characterize serum monoclonal protein.
Qualitative Immunofixation Electrophoresis/Quantitative Capillary Electrophoresis/Quantitative Immunoturbidimetry/Quantitative Spectrophotometry
Sun-Sat
1-5 days
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 2.5 mL serum to an ARUP Standard Transport Tube. (Min: 2.0 mL)
Refrigerated.
Plasma. Room temperature specimens.
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
Test Number |
Components |
Reference Interval |
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0050640 | Protein Electrophoresis, Serum | Effective August 19, 2019
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0050340 | Immunoglobulin A | Effective February 16, 2021
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0050350 | Immunoglobulin G | Effective February 16, 2021
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0050355 | Immunoglobulin M | Effective February 16, 2021
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Kappa Qnt Free Light Chains | Effective February 18, 2020 3.30 - 19.40 mg/L |
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Lambda Qnt Free Light Chains | Effective February 18, 2020 5.71-26.30 mg/L |
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Kappa/Lambda Free Light Chain Ratio | 0.26-1.65 |
Undetected antigen excess is a rare event but cannot be excluded. Free light chain results should always be interpreted in conjunction with other clinical and laboratory findings.
FDA
A copy of the graph will follow the final report. This assay is highly sensitive to increasing concentrations of monoclonal free kappa or free lambda light chains in the serum of patients with evolving or relapsing myelomas.
Hotline History
82784 x3; 84155; 84165; 86334; 83520 x2
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050020 | Albumin | 2862-1 |
0050035 | Alpha 1 Globulin | 2865-4 |
0050060 | Alpha 2 Globulin | 2868-8 |
0050110 | Beta Globulin | 2871-2 |
0050270 | Gamma | 2874-6 |
0050271 | Immunofixation | 25700-6 |
0050340 | Immunoglobulin A | 2458-8 |
0050350 | Immunoglobulin G | 2465-3 |
0050355 | Immunoglobulin M | 2472-9 |
0050545 | Total Protein, Serum | 2885-2 |
0055168 | Kappa Qnt Free Light Chains | 36916-5 |
0055169 | Lambda Qnt Free Light Chains | 33944-0 |
0055179 | Kappa/Lambda Free Light Chain Ratio | 80517-6 |
2005168 | SPEP/IFE Interpretation | 49275-1 |
2012457 | EER Monoclonal Protein and FLC, Serum |
- IFE
- IgA, IgG, and IgM
- Immunofixation, serum
- Kappa Qnt Free Light Chains
- Kappa/Lambda Free Light Chain Ratio
- Kappa/Lambda Free Light Chains
- Lambda Qnt Free Light Chains
- MGUS study
- Monoclonal Protein Study
- Mutiple Myeloma Study
- SPEP