Detect aneuploidy for chromosomes 3, 7, and 17. Use in conjunction with current standard diagnostic procedures as an aid for diagnosis of pancreatic cancer.
Fluorescence in situ Hybridization (FISH)/Computer Assisted Analysis/Microscopy
New York DOH Approval Status
Bile or pancreatic duct brushings, biliary stent, or fine needle aspirates of the pancreas in UroVysion FISH Collection Kit (ARUP Supply #41440) available online through eSupply using ARUP Connector contact Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection & Handling.
Place specimen in Cytolyt or PreservCyt fixative vial. If the specimen is a brushing, submit the brush in the fixative. Specimen should be placed in fixative vial immediately after collection.
Ambient or Refrigerated.
Frozen specimens. Unfixed specimens not collected in Cytolyt or PreservCyt fixative. Specimens submitted in expired collection vials.
Specimen source is required.
Ambient: 1 week from collection; Refrigerated: 1 week from collection; Frozen: Unacceptable
|Positive||≥5 cells with gains of two or more chromosomes are present|
|Equivocal Tetrasomy||Cells present with tetrasomic or near tetrasomic signal patterns|
|Equivocal Trisomy||≥10 cells with gains of a single chromosome, (Trisomy 7 or Trisomy 3)|
|Negative||< 5 abnormal cells are present|
Refer to Report.
Laboratory Developed Test (LDT)
The UroVysion Kit (ARUP Supply #41440) is designed to detect aneuploidy for chromosomes 3, 7 and 17via fluorescence in situ hybridization (FISH). Results of this test must be interpreted in conjunction with clinical evidence and other laboratory testing and should not be used alone,as a diagnosis of pancreatobiliary carcinoma.
|Component Test Code*||Component Chart Name||LOINC|
|2002452||Pancreatobiliary FISH Specimen Source||66746-9|
|2002459||Pancreatobiliary FISH Clinical History||22636-5|
|2002463||Pancreatobiliary FISH Gross Description||22634-0|
- Bile Duct FISH
- Bile Duct Tumor
- Biliary Tract Malignancy FISH
- Cholangiocarcinoma FISH
- Pancreas FISH