Ordering Recommendation

Aid in the diagnosis of invasive/disseminated fungal infections (eg, P. jirovecii, Aspergillus, or Candida).

Mnemonic
BDGLUCAN
Methodology

Semi-Quantitative Colorimetry

Performed

Mon-Fri

Reported

Within 3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to a sterile ARUP Standard Transport Tube (ARUP supply # 43115) available online through eSupply using ARUP Connect ™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Specimen types other than those listed. Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks

Reference Interval

Less than 31 pg/mL: Negative
31-59 pg/mL: Negative
60-79 pg/mL: Indeterminate
Greater than or equal to 80 pg/mL: Positive

Interpretive Data

The Fungitell test is indicated for presumptive diagnosis of fungal infection and should be used in conjunction with other diagnostic procedures. This test does not detect certain fungal species such as Cryptococcus, which produce very low levels of (1,3)-beta-D-glucan. This test will not detect the zygomycetes, such as Absidia, Mucor, and Rhizopus, which are not known to produce (1,3)-beta-D-glucan. In addition, the yeast phase of Blastomyces dermatitidis produces little (1,3)-beta-D-glucan and may not be detected by the assay.

Compliance Category

FDA

Note

Reference ranges for pediatric patients (less than 18 years old) have not been established. Assay ranges were validated in adult subjects.

Hotline History
N/A
CPT Codes

87449

Components
Component Test Code* Component Chart Name LOINC
2002435 (1,3)-beta-D-glucan Interpretation
2002436 (1,3)-beta-D-glucan 42176-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Beta-D glucan
  • Fungitell
  • Glucan
(1,3)-Beta-D-Glucan (Fungitell)