Aid in diagnosis and classification of hematopoietic neoplasms presenting with prominent eosinophilia. Does not detect rearrangements associated with chronic myelogenous leukemia.
Fluorescence in situ Hybridization (FISH)
Non-diluted bone marrow aspirate collected in a heparinized syringe. Also acceptable: Green (Sodium Heparin).
Bone Marrow: Transfer 3 mL bone marrow to a Green (Sodium Heparin) (Min: 1 mL).
Whole Blood: Transport 5 mL whole blood. (Min: 2 mL)
Paraffin-embedded specimens. Clotted specimens.
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Probes included: PDGFR-alpha, PDGFR-beta, FGFR1, and CBFB.
Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.
A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
88271 x4; 88275 x4; 88291
|Component Test Code*||Component Chart Name||LOINC|
|2002379||Eosinophilia Panel by FISH|
|2002380||EER FISH EOS P|
- FISH, Myeloproliferative Neoplasms (Eosinophilia)