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PML-RARA Translocation by FISH
Ordering Recommendation
Rapid confirmatory diagnostic test for APL.
Methodology
Fluorescence in situ Hybridization (FISH)
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
Specimen Required
Non-diluted bone marrow collected in a heparinized syringe. Also acceptable: Green (sodium heparin).
Transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL). OR transport 5 mL whole blood (Min: 2 mL).
Room temperature.
Frozen specimens. Paraffin-embedded specimens. Clotted specimens.
Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Reference Interval
By report
Interpretive Data
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Analyte Specific Reagent (ASR)
Note
A processing fee will be charged if this procedure is canceled, at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.
If cell pellets or dropped cytogenetics slides are submitted, a processing fee will not apply.
This test must be ordered using Oncology test request form #43099 or through your ARUP interface.
Hotline History
CPT Codes
88271; 88275
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2002364 | PML-RARA Translocation by FISH | 57802-1 |
| 2002365 | EER PML-RARA Translocation by FISH | 11526-1 |
Aliases
- t(15;17)
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