Ordering Recommendation

Initial test to diagnose or rule out creatine deficiency syndromes following clinical presentation. Order Creatine Disorders Panel, Serum or Plasma (2002328), simultaneously for proper result interpretation.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Random urine.

Specimen Preparation

Transfer 2 mL urine to an ARUP standard transport tube and freeze immediately. (Min: 0.5 mL)

Storage/Transport Temperature


Unacceptable Conditions

Clinical information is needed for appropriate interpretation. Additional required information includes age, gender, diet (e.g., TPN therapy), drug therapy, and family history. Biochemical Genetics Patient History Form is available on the ARUP Web site at https://www.aruplab.com/patienthistory or by contacting ARUP Client Services.


Ambient: 6 hours; Refrigerated: 24 hours; Frozen: 6 months (Three freeze/thaw cycles are acceptable.)


Liquid Chromatography-Tandem Mass Spectrometry


Mon, Thu


2-9 days

Reference Interval

Refer to report

Interpretive Data

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

82540; 82570; 82542


Component Test Code* Component Chart Name LOINC
2002334 Creatinine, Urine 14683-7
2002336 Guanidinoacetic acid, Urine 34155-2
2002338 Creatine, Urine 34275-8
2002339 Creatine Disorder Urine Interpretation
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • AGAT
  • GAA & Creatine
  • GAA + Creatine
  • GAMT
  • Guanidinoacetic Acid + Creatine
  • Guanidnoacetic Acid & Creatine
Creatine Disorders Panel, Urine