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Time Sensitive

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Cytogenetic Test Request Form Recommended (ARUP form #43098)
Ordering Recommendation

Prenatal chromosome analysis on amniotic fluid when individual
• Is at increased risk for fetal aneuploidy based on maternal age, abnormal noninvasive prenatal testing (NIPT), abnormal multiple marker screening, or abnormal fetal ultrasound.
• Has a family history of chromosome abnormality or genetic disorder.
• Desires diagnostic testing instead of screening.

Mnemonic
CHR AF
Methodology

Giemsa Band

Performed

Sun-Sat

Reported

7-14 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Amniotic fluid.

Specimen Preparation

Do not freeze or expose to extreme temperatures. Transport 30 mL amniotic fluid in a sterile container. (Min: 15 mL)

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Frozen specimens. Bloody specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report

Compliance Statement C: For human genetic inheritable conditions and mutations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Note

These studies involve culturing of living cells; therefore, turnaround times given represent average times which are subject to multiple variables. Results are generally available in an average of 12 days after receipt of a specimen.

A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth.

Specimen and completed test request form, including clinical indication, must be received within 48 hours of collection.

This test must be ordered using Cytogenetic test request form #43098 or through your ARUP interface. Please submit the Patient History for Prenatal Cytogenetics form with the electronic packing list (https://ltd.aruplab.com/Tests/Pdf/65).

Hotline History
N/A
CPT Codes

88269; 88235; 88291

Components
Component Test Code* Component Chart Name LOINC
0097601 Chromosome Analysis, Amniotic Fluid 33773-3
2002199 EER Chromosome Analysis Amniotic Fluid
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Karyotype, Amniotic Fluid
  • NIPD confirmation study
  • NIPT confirmation study
  • Prenatal Diagnosis, Amniotic Fluid, Prenatal Chromosomes, Amniotic Fluid
Chromosome Analysis, Amniotic Fluid