2002291
print

Chromosome Analysis, Chorionic Villus

CHR CVS
Example Reports
Abnormal
Enhanced Report
Normal

Icon

Time Sensitive

Icon

Cytogenetic Test Request Form Recommended (ARUP form #43098)

Icon

Informed Consent for Genetic Testing (required for NY patients)

Icon

Prenatal Cytogenetics Patient History Form

Ordering Recommendation

Prenatal chromosome analysis on chorionic villi when individual
• Is at increased risk for fetal aneuploidy based on maternal age, abnormal noninvasive prenatal testing (NIPT), abnormal multiple marker screening, or abnormal fetal ultrasound.
• Has a family history of chromosome abnormality or genetic disorder.
• Desires diagnostic testing instead of screening.

Methodology

Giemsa Band

Performed

Sun-Sat

Reported

7-14 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Thaw media prior to collection.

Specimen Preparation

DO NOT FREEZE. Do not place in formalin. Transport chorionic villus (CVS) specimen in a sterile, screw-top container filled with tissue culture transport medium.

Storage/Transport Temperature

Room temperature

Unacceptable Conditions

Frozen specimens. Specimens preserved in formalin.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

Refer to report

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Counseling and informed consent are recommended for genetic testing. Consent forms are available online.

Compliance Category

Laboratory Developed Test (LDT)

Note

These studies involve culturing of living cells; therefore, turnaround times given represent average times, which are subject to multiple variables.

A processing fee to cover sex confirmation and rule out maternal contamination by FISH is added to all Chromosome Analysis, Chorionic Villus Sampling (CVS) tests. An additional processing fee will be charged if this procedure is canceled at the client's request after the test has been set up or if the specimen integrity is inadequate to allow culture growth.

Chorionic villus in a sterile, screw-top container filled with tissue culture transport medium (ARUP Supply #32788). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. If cytogenetics tissue media is not available, collect in plain RPMI, Hanks solution, saline, or ringers.

If specimen size is too large for a normal collection tube, a larger sterile container can be used such as a sterile urine cup and can be flooded with several tubes of cytogenetic tissue media.

This test must be ordered using Cytogenetic test request form #43098 or through your ARUP interface. Please submit the Patient History for Prenatal Cytogenetics form with the electronic packing list (https://ltd.aruplab.com/Tests/Pdf/65).

Hotline History

N/A

CPT Codes

88267; 88235

Are you an ARUP Client? Click here for your pricing.

Components

Component Test Code* Component Chart Name LOINC
0097610 Chromosome Analysis, Chorionic Villus 33774-1
2002201 EER Chromosome Analysis Chorionic Villus 11502-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • chorionic villi
  • Karyotype, CVS
  • NIPD confirmation study
  • NIPT confirmation study
  • Prenatal Chromosomes, CVS
  • Prenatal Diagnosis, CVS, Chromosome Analysis
  • villi
Chromosome Analysis, Chorionic Villus