Aid in the diagnosis of monoclonal gammopathies, including multiple myeloma, when clinical pretest probability is low. Use to detect and quantify serum monoclonal protein. Immunofixation is performed if patterns from SPEP are monoclonal or suspicious.
Quantitative Capillary Electrophoresis/Qualitative Immunofixation Electrophoresis/Quantitative Nephelometry/Quantitative Spectrophotometry
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 1.5 mL)
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
|0050640||Protein Electrophoresis, Serum||Effective August 19, 2019
|0050340||Immunoglobulin A||Effective February 16, 2016
|0050355||Immunoglobulin M||Effective February 16, 2016
Immunofixation electrophoresis is a more sensitive technique than serum protein electrophoresis for the identification of small M-proteins found in patients with amyloidosis, early or treated myeloma and macroglobulinemia, MGUS, solitary plasmacytoma, and extramedullary plasmacytoma.
If patterns from serum protein electrophoresis are monoclonal or suspicious, then Immunofixation Electrophoresis will be added. Additional charges apply.
IFE is a more sensitive method for determining and defining monoclonal proteins. No additional testing will be added for proteins that are normal, polyclonal, or that lack monoclonal patterns.
84155; 84165; if reflexed, add 82784 x3; 86334
|Component Test Code*||Component Chart Name||LOINC|
|0050035||Alpha 1 Globulin||2865-4|
|0050060||Alpha 2 Globulin||2868-8|
|0050545||Total Protein, Serum||2885-2|
|2012455||EER Serum Protein Electrophoresis Reflex||11526-1|
- Electrophoresis, Protein, Serum with Reflex to Immunofixation Electrophoresis
- IFE Reflex
- MGUS study
- Monoclonal protein detection
- Monoclonal Protein Study
- Multiple Myeloma Study
- Protein Electrophoresis with Interpretation, Serum and Reflex to IFE and QNTIG's
- Protein Electrophoresis, Serum with Reflex to IFE, Serum
- Protein Electrophoresis, with Interpretation Serum, With Reflex to IFE, Serum