Aid in the diagnosis and management of monoclonal gammopathies. Use to detect and quantify serum monoclonal protein. Immunofixation is performed if patterns observed in protein electrophoresis p are monoclonal or suspicious.
Quantitative Capillary Electrophoresis/Qualitative Immunofixation Electrophoresis/Quantitative Immunoturbidimetry/Quantitative Spectrophotometry
New York DOH Approval Status
Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 1.5 mL serum to an ARUP Standard Transport Tube. (Min: 1.5 mL)
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 1 month
|0050640||Protein Electrophoresis, Serum||Effective August 19, 2019
|0050350||Immunoglobulin G||Effective February 16, 2021
|0050340||Immunoglobulin A||Effective February 16, 2021
|0050355||Immunoglobulin M||Effective February 16, 2021
Serum protein electrophoresis, when used as a screening test, is useful in the detection of various pathophysiologic states such as inflammation, protein loss, gammopathies, and other dysproteinemias. However, immunofixation electrophoresis (IFE) is a more sensitive technique for the identification of small M-proteins found in patients with amyloidosis, early or treated myeloma or macroglobulinemia, solitary plasmacytoma, or extramedullary plasmacytoma.
If patterns from serum protein electrophoresis are monoclonal or suspicious, then Immunofixation Electrophoresis will be added. Additional charges apply.
No additional testing will be added for proteins that are normal, polyclonal, or that lack monoclonal patterns.
84155; 84165; if reflexed, add 82784 x3; 86334
|Component Test Code*||Component Chart Name||LOINC|
|0050035||Alpha 1 Globulin||2865-4|
|0050060||Alpha 2 Globulin||2868-8|
|0050545||Total Protein, Serum||2885-2|
|2012455||EER Serum Protein Electrophoresis Reflex||11526-1|
- Electrophoresis, Protein, Serum with Reflex to Immunofixation Electrophoresis
- IFE Reflex
- MGUS study
- Monoclonal protein detection
- Monoclonal Protein Study
- Multiple Myeloma Study
- Protein Electrophoresis with Interpretation, Serum and Reflex to IFE and QNTIG's
- Protein Electrophoresis, Serum with Reflex to IFE, Serum
- Protein Electrophoresis, with Interpretation Serum, With Reflex to IFE, Serum