Hirsutism Evaluation Panel

2001763
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High
Normal
Ordering Recommendation

Aids in the detection and subclassification of hyperandrogenism. Most useful in women and children with moderate/severe hirsutism or hirsutism of any degree when it is sudden in onset or rapidly progressive.

Mnemonic
HIRSUTISM
Methodology

Quantitative Chemiluminescent Immunoassay/Electrochemiluminescent Immunoassay/Liquid Chromatography-Tandem Mass Spectrometry

Performed

Sun, Tue-Fri

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Collect between 6-10 a.m.

Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 2.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: 48 hours; Frozen: 2 months

Reference Interval
Test Number
 Components
 Reference Interval
2001638 Androstenedione Effective August 19, 2013
Age Female Male
Premature Infants, 26-28 weeks-Day 4 0.92-2.82 ng/mL 0.92-2.82 ng/mL
Premature Infants, 31-35 weeks-Day 4 0.80-4.46 ng/mL 0.80-4.46 ng/mL
Full-term Infants, 1-7 days 0.20-2.90 ng/mL 0.20-2.90 ng/mL
8-30 days 0.18-0.80 ng/mL 0.18-0.80 ng/mL
1-5 months 0.06-0.68 ng/mL 0.06-0.68 ng/mL
6-24 months Less than 0.15 ng/mL 0.03-0.15 ng/mL
2-3 years Less than 0.16 ng/mL Less than 0.11 ng/mL
4-5 years 0.02-0.21 ng/mL 0.02-0.17 ng/mL
6-7 years 0.02-0.28 ng/mL 0.01-0.29 ng/mL
8-9 years 0.04-0.42 ng/mL 0.03-0.30 ng/mL
10-11 years 0.09-1.23 ng/mL 0.07-0.39 ng/mL
12-13 years 0.24-1.73 ng/mL 0.10-0.64 ng/mL
14-15 years 0.39-2.00 ng/mL 0.18-0.94 ng/mL
16-17 years 0.35-2.12 ng/mL 0.30-1.13 ng/mL
18-39 years 0.26-2.14 ng/mL 0.33-1.34 ng/mL
40 years and older 0.13-0.82 ng/mL 0.23-0.89 ng/mL
Pre-menopausal 0.26-2.14 ng/mL Does Not Apply
Postmenopausal 0.13-0.82 ng/mL Does Not Apply
Tanner Stage I 0.05-0.51 ng/mL 0.04-0.32 ng/mL
Tanner Stage II 0.15-1.37 ng/mL 0.08-0.48 ng/mL
Tanner Stage III 0.37-2.24 ng/mL 0.14-0.87 ng/mL
Tanner Stage IV-V 0.35-2.05 ng/mL 0.27-1.07 ng/mL

0070040 Dehydroepiandrosterone Sulfate, Serum
Age
 Male
 Female
0-6 days
7-30 days
1-5 months
6-35 months
3-6 years
7-9 years
10-14 years
15-19 years
20-29 years
30-39 years
40-49 years
50-59 years
60-69 years
70 years and older		 108-607 µg/dL
32-431 µg/dL
3-124 µg/dL
0-33 µg/dL
0-44 µg/dL
5-115 µg/dL
22-332 µg/dL
88-483 µg/dL
280-640 µg/dL
120-520 µg/dL
95-530 µg/dL
70-310 µg/dL
42-290 µg/dL
28-175 µg/dL		 108-607 µg/dL
32-431 µg/dL
3-124 µg/dL
0-29 µg/dL
0-47 µg/dL
5-94 µg/dL
22-255 µg/dL
63-373 µg/dL
65-380 µg/dL
45-270 µg/dL
32-240 µg/dL
26-200 µg/dL
13-130 µg/dL
10-90 µg/dL
Tanner Stage I
Tanner Stage II
Tanner Stage III
Tanner Stage IV & V		 7-209 µg/dL
28-260 µg/dL
39-390 µg/dL
81-488 µg/dL		 7-126 µg/dL
13-241 µg/dL
32-446 µg/dL
65-371 µg/dL

0081059 Testosterone Free, Females or Children
Female Free Testosterone, pg/mL
 Male Free Testosterone, pg/mL
1-6 years: Less than 0.6 pg/mL
7-9 years: 0.6-1.8 pg/mL
10-11 years: 0.1-3.5 pg/mL
12-13 years: 0.9-6.8 pg/mL
14-15 years: 1.2-7.5 pg/mL
16-17 years: 1.2-9.9 pg/mL
18-30 years: 0.8-7.4 pg/mL
31-40 years: 1.3-9.2 pg/mL
41-51 years: 1.1-5.8 pg/mL
Postmenopausal: 0.6-3.8 pg/mL
Tanner Stage I: Less than 2.2 pg/mL
Tanner Stage II: 0.4-4.5 pg/mL
Tanner Stage III: 1.3-7.5 pg mL
Tanner Stage IV: 1.1-15.5 pg/mL
Tanner Stage V: 0.8-9.2 pg/mL		 1-6 years: Less than 0.6 pg/mL
7-9 years: 0.1-0.9 pg/mL
10-11 years: 0.1-6.3 pg/mL
12-13 years: 0.5-98.0 pg/mL
14-15 years: 3-138.0 pg/mL
16-17 years: 38.0-173.0 pg/mL
18 years and older: 47-244 pg/mL
Tanner Stage I: Less than or equal to 3.7 pg/mL
Tanner Stage II: 0.3-21 pg/mL
Tanner Stage III: 1.0-98.0 pg mL
Tanner Stage IV: 35.0-169.0 pg/mL
Tanner Stage V: 41.0-239.0 pg/mL

0081058 Testosterone, Females or Children Effective August 19, 2013
Age
 Female
 Male
Premature (26-28 weeks) 5-16 ng/dL 59-125 ng/dL
Premature (31-35 weeks) 5-22 ng/dL 37-198 ng/dL
Newborn 20-64 ng/dL 75-400 ng/dL
1-5 months Less than 20 ng/dL 14-363 ng/dL
6-24 months Less than 9 ng/dL Less than 37 ng/dL
2-3 years Less than 20 ng/dL Less than 15 ng/dL
4-5 years Less than 30 ng/dL Less than 19 ng/dL
6-7 years Less than 7 ng/dL Less than 13 ng/dL
8-9 years 1-11ng/dL 2-8 ng/dL
10-11 years 3-32 ng/dL 2-165 ng/dL
12-13 years 6-50 ng/dL 3-619 ng/dL
14-15 years 6-52 ng/dL 31-733 ng/dL
16-17 years 9-58 ng/dL 158-826 ng/dL
18-39 years 9-55 ng/dL 300-1080 ng/dL
40-59 years 9-55 ng/dL 300-890 ng/dL
60 years and older 5-32 ng/dL 300-720 ng/dL
Premenopausal (18 years and older) 9-55 ng/dL Does Not Apply
Postmenopausal 5-32 ng/dL Does Not Apply
Tanner Stage I 2-17 ng/dL 2-15 ng/dL
Tanner Stage II 5-40 ng/dL 3-303 ng/dL
Tanner Stage III 10-63 ng/dL 10-851 ng/dL
Tanner Stage IV-V 11-62 ng/dL 162-847 ng/dL

0099375 Sex Hormone Binding Globulin
Age Male Female
1-30 days
31-364 days
1-3 years
4-6 years
7-9 years
10-12 years
13-15 years
16-17 years
18 years and older		 13-85 nmol/L
70-250 nmol/L
50-180 nmol/L
45-175 nmol/L
28-190 nmol/L
23-160 nmol/L
13-140 nmol/L
10-60 nmol/L
11-80 nmol/L		 14-60 nmol/L
60-215 nmol/L
60-190 nmol/L
55-170 nmol/L
35-170 nmol/L
17-155 nmol/L
11-120 nmol/L
19-145 nmol/L
30-135 nmol/L
Tanner Stage I
Tanner Stage II
Tanner Stage III
Tanner Stage IV
Tanner Stage V		 26-186 nmol/L
22-169 nmol/L
13-104 nmol/L
11-60 nmol/L
11-71 nmol/L		 30-173 nmol/L
16-127 nmol/L
12-98 nmol/L
14-151 nmol/L
23-165 nmol/L

Interpretive Data



Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

82157; 82627; 84403; 84270

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Components
Component Test Code* Component Chart Name LOINC
0070040 DHEAS 2191-5
0081058 Testosterone, LC-MS/MS 2986-8
0081096 Testosterone, Free LC-MS/MS 2991-8
0099375 Sex Hormone Binding Globulin 13967-5
2001639 Androstenedione by TMS 1854-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Hirsutism Evaluation Panel