Fetal Hemoglobin Determination for Fetomaternal Hemorrhage
Ordering Recommendation
Detect and quantify the extent of fetomaternal hemorrhage in pregnant or postpartum women. Assess the need for Rh immunoglobulin (eg, RhoGAM) for fetomaternal hemorrhage.
New York DOH Approval Status
Specimen Required
Maternal, pregnant or postpartum whole blood.
Lavender (EDTA) or pink (K2EDTA).
New York State Clients: Lavender (EDTA). Collect and ship Monday-Thursday only. Ship same day as collection.
Transport 5 mL whole blood. (Min: 0.5 mL)
New York State Clients: Transport 5 mL whole blood. (Min: 1 mL)
Refrigerated.
Clotted or hemolyzed specimens. Refrigerated specimens greater than 120 hours (5 days) old; Ambient specimens greater than 12 hours old. Specimens from males or nonpregnant females.
Ambient: 12 hours; Refrigerated: 120 (5 days) hours; Frozen: Unacceptable
Methodology
Quantitative Flow Cytometry
Performed
Sun-Sat
Reported
1-2 days
Reference Interval
0.000-0.124%
Interpretive Data
Result |
Interpretation |
---|---|
% Fetal RBCs | The fetal RBC percentage is directly measured by flow cytometry and gives the percentage of fetal RBCs in the maternal circulation resulting from recent fetal-maternal hemorrhage. For accurate calculation of RhIG dosage that includes maternal height and weight, please refer to the most recent AABB Technical Manual. |
Laboratory Developed Test (LDT)
Note
This test should only be used to detect and quantify the extent of fetomaternal hemorrhage, in pregnant or postpartum women who need to be assessed for Rh immune globulin (e.g. RhoGAM®) or fetal-maternal bleeds.
For routine fetal hemoglobin (Hb F) testing, please order Hemoglobin Evaluation with Reflex to Electrophoresis and/or RBC Solubility (ARUP test code 0050610).
Hotline History
Hotline History
CPT Codes
86356
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2001788 | Fetal Hgb - Percent Fetal RBCs | 55729-8 |
Aliases
- Fetal Hemoglobin
- Fetal Maternal Bleed
- Fetal Maternal Erythrocyte Distribution, Blood
- Fetal-Maternal Erythrocyte Differentiation
- Fetomaternal Bleed by Flow Cytometry (Blood)
- Kleihauer Acid Elution (Fetal RBCs)
- Kleihauer-Betke
- Kleihauer-Betke Acid Elution for Fetal RBC Detection
- Maternal Erythrocyte Diff
- RhoGAM determination