Fetal Hemoglobin Determination for Fetomaternal Hemorrhage

2001743
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Example Reports
Abnormal
Normal

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Time Sensitive

Ordering Recommendation

Detect and quantify the extent of fetomaternal hemorrhage in pregnant or postpartum women. Assess the need for Rh immunoglobulin (eg, RhoGAM) for fetomaternal hemorrhage.

Mnemonic

FHGB

Methodology

Quantitative Flow Cytometry

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation

Maternal, pregnant or post-partum whole blood.

Collect

Lavender (EDTA) or pink (K2EDTA).
New York State Clients: Lavender (EDTA). Collect and ship Monday-Thursday only. Ship same day as collection.

Specimen Preparation

Transport 5 mL whole blood. (Min: 0.5 mL)
New York State Clients: Transport 5 mL whole blood. (Min: 1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Clotted or hemolyzed specimens. Refrigerated specimens greater than 120 hours (5 days) old; Ambient specimens greater than 12 hours old. Specimens from males or non-pregnant females.

Remarks
Stability

Ambient: 12 hours; Refrigerated: 120 (5 days) hours; Frozen: Unacceptable

Reference Interval

By report

Interpretive Data

The performance characteristics of this test were determined by ARUP Laboratories, Inc.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Result
 Interpretation
% Fetal RBCs The fetal RBC percentage is directly measured by flow cytometry and gives the percentage of fetal RBCs in the maternal circulation resulting from recent fetal-maternal hemorrhage. Post-partum, some fetal cells are expected (0.04% plus or minus 0.024%, mean plus or minus SD). For accurate calculation of RhIG dosage that includes maternal height and weight, please refer to the most recent AABB Technical Manual.

Compliance Category

Laboratory Developed Test (LDT)

Note

This test should only be used to detect and quantify the extent of fetomaternal hemorrhage, in pregnant or post-partum women who need to be assessed for Rh immune globulin (e.g. RhoGAM®) or fetal-maternal bleeds. 

For routine fetal hemoglobin (Hb F) testing, please order Hemoglobin Evaluation with Reflex to Electrophoresis and/or RBC Solubility (0050610).

Hotline History

N/A

CPT Codes

86356

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Components

Component Test Code* Component Chart Name LOINC
2001788 Fetal Hgb - Percent Fetal RBCs 55729-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Fetal Hemoglobin
  • Fetal Maternal Bleed
  • Fetal Maternal Erythrocyte Distribution, Blood
  • Fetal-Maternal Erythrocyte Differentiation
  • Fetomaternal Bleed by Flow Cytometry (Blood)
  • Kleihauer Acid Elution (Fetal RBCs)
  • Kleihauer-Betke
  • Kleihauer-Betke Acid Elution for Fetal RBC Detection
  • Maternal Erythrocyte Diff
  • RhoGAM determination
Fetal Hemoglobin Determination for Fetomaternal Hemorrhage