Ordering Recommendation
Detect and quantify the extent of fetomaternal hemorrhage in pregnant or postpartum women. Assess the need for Rh immunoglobulin (eg, RhoGAM) for fetomaternal hemorrhage.
Mnemonic
Methodology
Quantitative Flow Cytometry
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Maternal, pregnant or post-partum whole blood.
Lavender (EDTA) or pink (K2EDTA).
New York State Clients: Lavender (EDTA). Collect and ship Monday-Thursday only. Ship same day as collection.
Transport 5 mL whole blood. (Min: 0.5 mL)
New York State Clients: Transport 5 mL whole blood. (Min: 1 mL)
Refrigerated.
Clotted or hemolyzed specimens. Refrigerated specimens greater than 120 hours (5 days) old; Ambient specimens greater than 12 hours old. Specimens from males or non-pregnant females.
Ambient: 12 hours; Refrigerated: 120 (5 days) hours; Frozen: Unacceptable
Reference Interval
By report
Interpretive Data
The performance characteristics of this test were determined by ARUP Laboratories, Inc.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Result |
Interpretation |
---|---|
% Fetal RBCs | The fetal RBC percentage is directly measured by flow cytometry and gives the percentage of fetal RBCs in the maternal circulation resulting from recent fetal-maternal hemorrhage. Post-partum, some fetal cells are expected (0.04% plus or minus 0.024%, mean plus or minus SD). For accurate calculation of RhIG dosage that includes maternal height and weight, please refer to the most recent AABB Technical Manual. |
Laboratory Developed Test (LDT)
Note
This test should only be used to detect and quantify the extent of fetomaternal hemorrhage, in pregnant or post-partum women who need to be assessed for Rh immune globulin (e.g. RhoGAM®) or fetal-maternal bleeds.
For routine fetal hemoglobin (Hb F) testing, please order Hemoglobin Evaluation with Reflex to Electrophoresis and/or RBC Solubility (0050610).
Hotline History
CPT Codes
86356
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
2001788 | Fetal Hgb - Percent Fetal RBCs | 55729-8 |
Aliases
- Fetal Hemoglobin
- Fetal Maternal Bleed
- Fetal Maternal Erythrocyte Distribution, Blood
- Fetal-Maternal Erythrocyte Differentiation
- Fetomaternal Bleed by Flow Cytometry (Blood)
- Kleihauer Acid Elution (Fetal RBCs)
- Kleihauer-Betke
- Kleihauer-Betke Acid Elution for Fetal RBC Detection
- Maternal Erythrocyte Diff
- RhoGAM determination