Optimize drug therapy and monitor patient adherence.
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Tue, Thu, Sat
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration. Blood levels may be affected by other concurrent medications, patient conditions, fat intake at dosing, and other factors.
Plain Red, Lavender (EDTA), or Green (Sodium or Lithium Heparin).
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube and freeze. (Min: 0.6 mL)
Serum separator tubes. Hemolyzed or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: 6 months
Effective August 15, 2011
Therapeutic Range (trough): Greater than 0.7 µg/mL
Adverse effects may include fever, nausea, vomiting, diarrhea, cardiac arrhythmias and liver toxicity.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|2001740||Posaconazole, Quantitative by LC-MS/MS||53731-6|
- noxafil blood level
- posaconazole blood level