Ordering Recommendation

Aid in the diagnosis of lymphocytic choriomeningitis (LCM) viral infection in CNS.

Mnemonic
LCM CSF
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or heat-inactivated specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
2001629 Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgG, CSF < 1:1 Negative - No significant level of LCM virus IgG antibody detected.
≥ 1:1 Positive - Presence of IgG antibody to LCM virus detected, suggestive of current or past infection.
2001630 Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgM, CSF < 1:1 Negative - No significant level of LCM virus IgM antibody detected.
≥ 1:1 Positive - Presence of IgM antibody to LCM virus detected, suggestive of current or past infection.

Interpretive Data

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Compliance Statement D: For laboratory tests using a manufactured RUO kit. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

86727 x2

Components
Component Test Code* Component Chart Name LOINC
2001631 LCM Virus Ab, IgG, CSF 9766-7
2001632 LCM Virus Ab, IgM, CSF 9768-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • LCM Antibodies, CSF
Lymphocytic Choriomeningitis (LCM) Virus Antibodies, IgG & IgM, CSF