Ordering Recommendation

Aid in the diagnosis of lymphocytic choriomeningitis (LCM) viral infection in CNS.

New York DOH Approval Status

This test is not New York state approved. There are no New York state-approved laboratories available. Submit a Non-Permitted Laboratory Request Form (NPL) to the NYDOH prior to collection of specimen. If NPL is approved by NYDOH, and sample is received at ARUP, testing will be performed.

Specimen Required

Patient Preparation


Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min 0.2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Contaminated, hemolyzed, or heat-inactivated specimens.


Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)


Semi-Quantitative Indirect Fluorescent Antibody


Tue, Fri


1-5 days

Reference Interval

Test Number
Reference Interval
  LCM Virus Ab, IgG, CSF Less than 1:1
  LCM Virus Ab, IgM, CSF Less than 1:1

Interpretive Data

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgG, CSF < 1:1 Negative - No significant level of LCM virus IgG antibody detected.
≥1:1 Positive - Presence of IgG antibody to LCM virus detected, suggestive of current or past infection.
Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgM, CSF < 1:1 Negative - No significant level of LCM virus IgM antibody detected.
≥1:1 Positive - Presence of IgM antibody to LCM virus detected, suggestive of current or past infection.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

86727 x2


Component Test Code* Component Chart Name LOINC
2001631 LCM Virus Ab, IgG, CSF 9766-7
2001632 LCM Virus Ab, IgM, CSF 9768-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • LCM Antibodies, CSF
Lymphocytic Choriomeningitis (LCM) Virus Antibodies, IgG & IgM, CSF