Ordering Recommendation

Aid in the diagnosis of lymphocytic choriomeningitis (LCM) viral infection in CNS.

Mnemonic
LCM CSF
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or heat-inactivated specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
2001629 Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgG, CSF < 1:1 Negative - No significant level of LCM virus IgG antibody detected.
≥ 1:1 Positive - Presence of IgG antibody to LCM virus detected, suggestive of current or past infection.
2001630 Lymphocytic Choriomeningitis (LCM) Virus Antibody, IgM, CSF < 1:1 Negative - No significant level of LCM virus IgM antibody detected.
≥ 1:1 Positive - Presence of IgM antibody to LCM virus detected, suggestive of current or past infection.

Interpretive Data

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

86727 x2

Components
Component Test Code* Component Chart Name LOINC
2001631 LCM Virus Ab, IgG, CSF 9766-7
2001632 LCM Virus Ab, IgM, CSF 9768-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • LCM Antibodies, CSF
Lymphocytic Choriomeningitis (LCM) Virus Antibodies, IgG & IgM, CSF