Ordering Recommendation

Aid in the diagnosis of infection with arboviruses.

Mnemonic
ARBOSER GM
Methodology

Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube. Also acceptable: Plain red.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective February 19, 2013

Components Reference Interval
St. Louis Encephalitis Antibody, IgG by IFA, Serum Less than 1:16
California Encephalitis Antibody, IgG by IFA, Serum Less than 1:16
Eastern Equine Encephalitis Antibody, IgG by IFA, Serum Less than 1:16
Western Equine Encephalitis Antibody, IgG by IFA, Serum Less than 1:16
West Nile Virus Antibody, IgG by ELISA, Serum 1.29 IV or less: Negative - No significant level of West Nile virus IgG antibody detected.
1.30-1.49 IV: Equivocal - Questionable presence of West Nile virus IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.50 IV or greater: Positive - Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.
St. Louis Encephalitis Antibody, IgM by IFA, Serum Less than 1:16
California Encephalitis Antibody, IgM by IFA, Serum Less than 1:16
Eastern Equine Encephalitis Antibody, IgM by IFA, Serum Less than 1:16
Western Equine Encephalitis Antibody, IgM by IFA, Serum Less than 1:16
West Nile Virus Antibody, IgM by ELISA, Serum 0.89 IV or less: Negative - No significant level of West Nile virus IgM antibody detected.
0.90-1.10 IV: Equivocal - Questionable presence of West Nile virus IgM antibody detected.  Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection.

Interpretive Data

Refer to report.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86651 x2; 86652 x2; 86653 x2; 86654 x2; 86789; 86788

Components
Component Test Code* Component Chart Name LOINC
0050234 West Nile Virus Ab, IgG, Ser 38997-3
0050236 West Nile Virus Ab, IgM, Ser 38166-5
0050507 St. Louis Encephalitis Ab, IgG, Serum 10906-6
0050508 Calif Encephalitis Antibody IgG 10904-1
0050509 Eastern Equine Enceph Ab, IgG 10896-9
0050514 Western Equine Enceph Ab, IgG, Serum 6957-5
0098731 California Encephalitis IgM 10905-8
0098732 St. Louis Encephalitis Ab, IgM, Serum 10907-4
0098733 Eastern Equine Enceph Ab, IgM 10898-5
0098734 Western Equine Enceph Ab, IgM, Ser 6958-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Arbovirus serology
  • California Encephalitis Antibody, IgG
  • California Encephalitis Antibody, IgM
  • Eastern Equine Encephalitis Antibody, IgG
  • Eastern Equine Encephalitis Antibody, IgM
  • Encephalitis Antibodies
  • St. Louis Encephalitis Antibody, IgG
  • St. Louis Encephalitis Antibody, IgM
  • West Nile Virus Antibody, IgG
  • West Nile Virus Antibody, IgM
  • Western Equine Encephalitis Antibody IgG
  • Western Equine Encephalitis, Antibody, IgM
Arbovirus Antibodies, IgG and IgM, Serum