Ordering Recommendation

Determine production of carbapenem-inactivating enzymes in gram negative bacterial organisms.

Mnemonic
MA KPC
Methodology

Disk Diffusion / Chromogenic Assay

Performed

Sun-Sat

Reported

2-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Actively growing Enterobacteriaceae species or Pseudomonas aeruginosa in pure culture.

Specimen Preparation

Transport sealed container with pure culture on agar slant or in bacterial transport media.  Place each specimen in an individually sealed bag.

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Mixed cultures or non-viable organisms.

Remarks

Isolate identification and specimen source required.

Stability

Ambient: 1 week; Refrigerated: 48 hours; Frozen: Unacceptable

Reference Interval

Negative

Interpretive Data

Carbapenemase production is a common mechanism of carbapenem resistance. For guidance on treatment of carbapenemase producers, consultation with an Infectious Disease physician is recommended.

Compliance Category

Standard

Note

An additional processing fee will be billed for all organisms not submitted in pure culture, as indicated in the specimen requirements.

If species identification is not provided, identification will be performed at ARUP. Additional charges apply.

Hotline History
N/A
CPT Codes

CPT codes vary based on method

Components
Component Test Code* Component Chart Name LOINC
2001503 Susceptibility, Carbapenemase
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Carbapenem resistance
  • carbapenem-resistance
  • carbapenems
  • Enterobacteriaceae
  • KPC
  • MDR
  • multi-drug resistance
  • NDM
  • New-Delhi metallo-B-lactamase
Antimicrobial Susceptibility - Carbapenemase Production