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Isohemagglutinin Titer, IgG and IgM
Ordering Recommendation
Aid in determination of the relative amount of anti-A or anti-B present in serum to evaluate an individual’s ability to mount an immune response. Most often performed on pediatric patients with recurrent infections.
Methodology
Hemagglutination
Performed
Mon-Fri
Reported
1-3 days
New York DOH Approval Status
Specimen Required
Lavender (K2EDTA), or Pink (K2EDTA).
Do not freeze. Transport 14 mL whole blood. (Min: 6 mL)
Refrigerated.
Separator or gel tubes.
Ambient: Unacceptable; Refrigerated: 1 week; Frozen: Unacceptable
Reference Interval
Normals are not applicable.
Interpretive Data
Standard
Note
Isohemagglutinin titers contain both IgM and IgG. Both IgG and IgM titers will be performed for this test. If only IgM or IgG titer is desired, order Isohemagglutinin Titer, IgG (2000271) or Isohemagglutinin Titer, IgM (2000270). Specimens are screened for antibodies; if positive, an antibody panel will be performed. Titers will be performed as indicated for specific blood groups. Additional charges will apply to antibody identification and titer testing.
Hotline History
CPT Codes
86900; if blood type is A add: 86886, 86941; if blood type is B, add: 86886, 86941; if blood type is O, add: 86886 x2, 86941 x2. If blood type is AB, no additional titers will be performed.
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2000288 | ABO Group ISO Interp | 883-9 |
| 2000289 | Anti A Titer IgM ISO | 50762-4 |
| 2000290 | Anti B Titer IgM ISO | 50763-2 |
| 2000295 | Anti A Titer IgG ISO | 50761-6 |
| 2000296 | Anti B Titer IgG ISO | 50764-0 |
Aliases
- Anti-A & B Titer
- Isohemagglutinin Titer Anti-A
- Isohemagglutinin Titer Anti-B
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