Ordering Recommendation

FDA-approved test for routine 3-year interval cervical cancer screening in all women ≥21 years. Optional to use for 3-year cervical cancer screening intervals in women 25-65 years; preferred cotesting panel is Cytology, SurePath Liquid-Based Pap Test and Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath (for routine cotesting in women over 30) (2000133).


Microscopy/ Qualitative Polymerase Chain Reaction




1-7 days, if reflexed, add 2 days

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation

Cervical specimen in a SurePath collection kit, Rovers Cervex-brush Kit (ARUP Supply #22216), PAP Perfect Plastic Spatula and Cytobrush Plus GT Collection Kit (ARUP Supply #41126), or Rovers Cervex-Brush Combi Collection Kit (ARUP Supply #45031) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection and Handling.

Specimen Preparation

Transport cervical specimen in the original collection kit.

Storage/Transport Temperature

Room temperature.

Unacceptable Conditions

Specimens not collected in a SurePath collection kit. Expired preservative vials or vials received without the collection devices.


Ambient: 1 month; Refrigerated: 6 months; Frozen: Unacceptable

Reference Interval
Interpretive Data

Refer to report.

No compliance statements are in use for this test.


If the SurePath Pap Test is interpreted as atypical squamous cells of undetermined significance (ASC-US), then Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath (ARUP test code 2011933) will be added. Additional charges apply.

Hotline History
CPT Codes

88142, if reviewed by pathologist add 88141.  If reflexed add 87624.

Component Test Code* Component Chart Name LOINC
2000507 SurePath Pap Reflex Specimen Source
2000508 SurePath Pap Reflex Clinical History
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • Pap Test
  • SurePath Pap reflex to HPV HR
  • SurePath Pap Test
  • SurePath Pap Test with reflex to HR HPV
Cytology, SurePath Liquid-Based Pap Test with Reflex to Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath