Ordering Recommendation

Acceptable test for routine cervical cancer screening at 3-year intervals in individuals 25-65 years of age with a cervix. Preferred test is Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath (2011933).






1-7 days
If reflexed, add 1-2 days.

New York DOH Approval Status

Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.

Specimen Required

Patient Preparation

Cervical specimen in a SurePath collection kit, Rovers Cervex-brush Kit (ARUP Supply #22216), PAP Perfect Plastic Spatula and Cytobrush Plus GT Collection Kit (ARUP Supply #41126), or Rovers Cervex-Brush Combi Collection Kit (ARUP Supply #45031) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection and Handling.

Specimen Preparation

Transport cervical specimen in the original collection kit.

Storage/Transport Temperature


Unacceptable Conditions

Specimens not collected in a SurePath collection vials. Specimens submitted in expired preservative collection vials. Collection vials received without the collection devices.


Ambient: 1 month; Refrigerated: 6 months; Frozen: Unacceptable

Reference Interval

Interpretive Data

Refer to report.

Compliance Category



If the SurePath Pap Test is interpreted as atypical squamous cells of undetermined significance (ASC-US), then Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath (ARUP test code 2011933) will be performed and reported under a separate accession. Additional charges apply.

The Pap Test is a screening test for cervical cancer and its precursors with an inherent false-negative rate.

Store collection vials without cytologic samples at room temperature (15°C to 30°C). Do not use solution beyond expiration date marked on the vial.

Hotline History


CPT Codes

88142, if reviewed by pathologist add 88141.  If reflexed add 87624.


Component Test Code* Component Chart Name LOINC
2000507 SurePath Pap Reflex Specimen Source
2000508 SurePath Pap Reflex Clinical History
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Pap Test
  • SurePath Pap reflex to HPV HR
  • SurePath Pap Test
  • SurePath Pap Test with reflex to HR HPV
Cytology, SurePath Liquid-Based Pap Test with Reflex to Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath