Ordering Recommendation

Acceptable test for routine cervical cancer screening at 3-year intervals in individuals 25-65 years of age with a cervix. Preferred test is Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath (2011933).

New York DOH Approval Status

This test is not New York state approved. ARUP cannot facilitate testing for New York state clients. Please work directly with a New York state-approved laboratory.

Specimen Required

Patient Preparation

Cervical specimen in a SurePath collection kit, Rovers Cervex-brush Kit (ARUP Supply #22216), PAP Perfect Plastic Spatula and Cytobrush Plus GT Collection Kit (ARUP Supply #41126), or Rovers Cervex-Brush Combi Collection Kit (ARUP Supply #45031) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection and Handling.

Specimen Preparation

Transport cervical specimen in the original collection kit.

Storage/Transport Temperature


Unacceptable Conditions

Specimens not collected in a SurePath collection vials. Specimens submitted in expired preservative collection vials. Collection vials received without the collection devices.


Ambient: 1 month; Refrigerated: 6 months; Frozen: Unacceptable






1-7 days
If reflexed, add 1-2 days.

Reference Interval

Interpretive Data

Refer to report.

Compliance Category



If the SurePath Pap Test is interpreted as atypical squamous cells of undetermined significance (ASC-US), then Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath (ARUP test code 2011933) will be performed and reported under a separate accession. Additional charges apply.

The Pap Test is a screening test for cervical cancer and its precursors with an inherent false-negative rate.

Store collection vials without cytologic samples at room temperature (15°C to 30°C). Do not use solution beyond expiration date marked on the vial.

Hotline History


CPT Codes

88142, if reviewed by pathologist add 88141.  If reflexed add 87624.


Component Test Code* Component Chart Name LOINC
2000507 SurePath Pap Reflex Specimen Source
2000508 SurePath Pap Reflex Clinical History
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Pap Test
  • SurePath Pap reflex to HPV HR
  • SurePath Pap Test
  • SurePath Pap Test with reflex to HR HPV
Cytology, SurePath Liquid-Based Pap Test with Reflex to Human Papillomavirus (HPV), High Risk with 16 and 18 Genotype by PCR, SurePath