Ordering Recommendation

FDA-approved test for routine cervical cancer screening at 3-year intervals in all individuals ≥21 years of age with a cervix. Acceptable test for routine cervical cancer screening at 3-year intervals in all individuals 25-65 years of age with a cervix; the preferred test for this group is Human Papillomavirus (HPV) High Risk with 16 and 18 Genotype by PCR, SurePath (2011933).

New York DOH Approval Status

This test is not New York state approved. ARUP cannot facilitate testing for New York state clients. Please work directly with a New York state-approved laboratory.

Specimen Required

Patient Preparation

Cervical specimen in a SurePath collection kit, Rovers Cervex-Brush Kit (ARUP Supply #22216), PAP Perfect Plastic Spatula and Cytobrush Plus GT Collection Kit (ARUP Supply #41126), or Rovers Cervex-Brush Combi Collection Kit (ARUP Supply #45031) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. For specific instructions refer to Specimen Collection and Handling.

Specimen Preparation

Transport cervical specimen in the original collection kit.

Storage/Transport Temperature


Unacceptable Conditions

Specimens not collected in a SurePath collection vial. Specimens submitted in expired preservative collection vials. Collection vials received without the collection devices.


Ambient: 1 month; Refrigerated: 6 months; Frozen: Unacceptable






1-7 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category



This test does NOT include HPV testing.

The Pap test is a screening test for cervical cancer and its precursors with an inherent false-negative rate.

Store collection vials without cytologic samples at room temperature (15°C to 30°C). Do not use solution beyond expiration date marked on the vial.

Hotline History


CPT Codes

88142; if reviewed by pathologist add 88141


Component Test Code* Component Chart Name LOINC
2000495 SurePath Pap Specimen Source 19763-2
2000496 SurePath Pap Clinical History 22636-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Cytology
  • Pap
  • Pap Smear
  • Pap Test
  • SurePath
  • SurePath Pap Test
Cytology, SurePath Liquid-Based Pap Test (Test on Delay as of 05/03/2024)