Ordering Recommendation

• Determine quantity of tissue plasminogen ( tPA) in plasma.
• May be helpful in detecting disorders of the fibrinolytic system.
• Not a first-line test for diagnosing inherited thrombotic or bleeding disorders.

Mnemonic
TPA AG
Methodology

Enzyme-Linked Immunosorbent Assay

Performed

Tue

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation

Separate plasma from cells and freeze ASAP. Transfer 1 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Serum, EDTA plasma, clotted or hemolyzed specimens.

Remarks
Stability

Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: 2 months

Reference Interval

Effective October 6, 2014
≤12.4 ng/mL

Interpretive Data



Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

85415

Components
Component Test Code* Component Chart Name LOINC
0099187 Tissue Plasminogen Activator Antigen 5971-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • TPA Antigen
Tissue Plasminogen Activator, Antigen