Ordering Recommendation

May be useful for detecting recent exposure.

Mnemonic
ANT B
Methodology

Quantitative Inductively Coupled Plasma-Mass Spectrometry

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Diet, medication, and nutritional supplements may introduce interfering substances. Patient should be encouraged to discontinue nutritional supplements, vitamins, minerals, and non-essential over-the-counter medications (upon the advice of their physician).

Collect

Glass BD Trace Element Free (K2EDTA or Na2EDTA) Tube.

Specimen Preparation

Transport whole blood in the original collection tube. (Min: 0.5 mL)

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated.

Unacceptable Conditions

Specimens collected in containers other than specified. Specimens transported in containers other than specified. Heparin anticoagulant. Clotted specimens.

Remarks
Stability

Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval

Less than or equal to 3.0 µg/L

Interpretive Data

Elevated results may be due to skin or collection-related contamination, including the use of a noncertified antimony-free collection tubes (including plastic BD Vacutainer Trace Element Tubes) or transport tube. If contamination concerns exist due to elevated levels of blood antimony, confirmation with a second specimen collected in a certified antimony-free tube is recommended.

Blood antimony levels predominantly reflect recent exposure and are most useful in the diagnosis of acute poisoning. Blood concentrations in unexposed individuals rarely exceed 3 µg/L. The form of antimony greatly influences distribution and elimination. Trivalent antimony readily enters red blood cells, has an extended half-life on the order of weeks to months, and is eliminated predominantly through the bile. Pentavalent antimony resides in the plasma, has a relatively short half-life on the order of hours to days, and is eliminated predominantly through the kidneys. Reported symptoms after toxic antimony exposure vary based upon route of exposure, duration and antimony source and may include abdominal pain, dyspnea, nausea, vomiting, dermatitis and eye irritation. Clinical presentation is similar to that of inorganic arsenic exposure.

Compliance Category

Laboratory Developed Test (LDT)

Note

BD Plastic Royal Blue (Na2EDTA/K2EDTA) collection tubes are not certified to be antimony-free.

Hotline History
N/A
CPT Codes

83018

Components
Component Test Code* Component Chart Name LOINC
0099007 Antimony Blood 5578-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ANTB
  • Sb
Antimony, Blood