Optimize drug therapy and monitor patient adherence.
Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2 EDTA).
Separate serum or plasma from cells within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).
After separation from cells: Ambient: 6 weeks; Refrigerated: 6 weeks; Frozen: 3 months (avoid repeated freeze/thaw cycles)
Effective November 18, 2013
|Therapeutic Range:||3-35 µg/mL|
|Toxic:||Greater than 40 µg/mL|
This test measures monohydroxyoxcarbazepine (MHD). Adverse effects may include dizziness, fatigue, nausea, headache, somnolence, ataxia and tremor.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|0098834||Oxcarb or Eslicarb Metabolite (MHD)||31019-3|
- 10-OH-Carbazepine (MHD)
- GP 47680
- Metabolite of Oxcarbazepine
- Monohydroxy Carbamazepine
- Monohydroxy Carbamazepine (MHD)
- Oxcarbazepine Metabolite
- Oxcarbazepine Metabolite, 10-Hydroxy-10
- Trileptal (Parent Pro-Drug)