Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

Mnemonic
OLANZ
Methodology

Quantitative Liquid Chromatography-Tandem Mass Spectrometry

Performed

Mon, Wed, Sat

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (K2 or K3EDTA) or pink (K2EDTA).

Specimen Preparation

Separate serum or plasma from cells within 2 hours of collection. Transport 2 mL serum or plasma. (Min: 1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Whole blood. Gel separator tubes, light blue (citrate), or yellow (SPS or ACD solution).

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

Effective November 18, 2013

Therapeutic Range: 20-80 ng/mL
Toxic: Not well established

Interpretive Data

Adverse effects may include dizziness, fatigue, somnolence and muscle weakness.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

80342 (Alt code: G0480)

Components
Component Test Code* Component Chart Name LOINC
0098833 Olanzapine 12389-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Symbyax
  • Zyprexa
  • zyprexa blood level
  • zyprexa zydis
Olanzapine (Temporary Referral as of 09/03/19)