Optimize drug therapy and monitor patient adherence.
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
Tue, Thu, Sat
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Plain Red, Lavender (EDTA), or Green (Sodium or Lithium Heparin).
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)
Serum separator tubes. Hemolyzed or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 48 hours; Frozen: 6 months
Effective August 15, 2011
|Itraconazole (trough) - Localized Infection||Greater than 0.5 µg/mL|
|Itraconazole (trough) - Systemic Infection||Greater than 1.0 µg/mL|
|Hydroxyitraconazole||No therapeutic range established|
Itraconazole and hydroxyitraconazole concentrations combined should not exceed 10 µg/mL. Adverse effects may include nausea, vomiting and rash.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|0098517||Itraconazole, Quantitative by LC-MS/MS||10989-2|
- Antifungal Serum Level
- itranconazole blood level
- sporanox blood concentration
- Sporanox blood level