Ordering Recommendation

Preferred second-line test when seronegative antiphospholipid syndrome (APS) is strongly suspected. Order incrementally or concurrently with other noncriteria antiphospholipid antibody tests.

Mnemonic
CARDIO IGA
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective August 18, 2014

0-11 APL Negative
12-19 APL Indeterminate
20-80 APL Low to Moderately Positive
81 APL or above High Positive

Interpretive Data



Compliance Category

FDA

Note

APL = IgA phospholipid units.

Hotline History
N/A
CPT Codes

86147

Components
Component Test Code* Component Chart Name LOINC
0098358 Cardiolipin Antibody IgA 5076-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • ACA
  • aCL Antibody
  • aCL IgA
  • Anticardiolipin Antibodies
  • Cardiolip
Cardiolipin Antibody, IgA