Ordering Recommendation
Preferred second-line test when seronegative antiphospholipid syndrome (APS) is strongly suspected. Order incrementally or concurrently with other noncriteria antiphospholipid antibody tests.
Mnemonic
CARDIO IGA
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Effective August 18, 2014
0-11 APL | Negative |
12-19 APL | Indeterminate |
20-80 APL | Low to Moderately Positive |
81 APL or above | High Positive |
Interpretive Data
Compliance Category
FDA
Note
APL = IgA phospholipid units.
Hotline History
N/A
CPT Codes
86147
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0098358 | Cardiolipin Antibody IgA | 5076-5 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- ACA
- aCL Antibody
- aCL IgA
- Anticardiolipin Antibodies
- Cardiolip
Cardiolipin Antibody, IgA