Ordering Recommendation

Preferred second-line test when seronegative antiphospholipid syndrome (APS) is strongly suspected. Order incrementally or concurrently with other noncriteria antiphospholipid antibody tests.

Mnemonic

CARDIO IGA

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective August 18, 2014

<=11 APL Negative
12-19 APL Indeterminate
20-80 APL Low to Moderately Positive
81 APL or above High Positive

Interpretive Data



Compliance Category

FDA

Note

APL = IgA phospholipid units.

Hotline History

N/A

CPT Codes

86147

Components

Component Test Code* Component Chart Name LOINC
0098358 Cardiolipin Antibody IgA 5076-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • ACA
  • aCL Antibody
  • aCL IgA
  • Anticardiolipin Antibodies
  • Cardiolip
Cardiolipin Antibody, IgA