Ordering Recommendation

Most useful to detect antibodies during acute phase of disease; recommend concurrent testing with IgG A. phagocyophilium. PCR testing is preferred; refer to Tick-Borne Disease Panel by PCR, Blood (2008670) or Ehrlichia and Anaplasma Species by PCR (2007862).

Mnemonic
HGE IGM
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Tue, Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Bacterially contaminated, heat inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

Less than 1:16 - No significant level of IgM antibodies to A. phagocytophilum detected.
Greater than or equal to 1:16 - Suggestive of a current or recent infection with A. phagocytophilum.

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

86666

Components
Component Test Code* Component Chart Name LOINC
0097318 A. Phagocytophilum Antibody, IgM 23878-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Anaplasma phagocytophilum (HGA) Antibody, IgM