Ordering Recommendation

Acceptable test for acute or convalescent phase of infection from Anaplasma phagocytophilium. May be useful when PCR testing is not an option (eg, outside the 2 week window for acute phase). However, PCR testing is generally preferred; refer to Tick-Borne Disease Panel by PCR, Blood (2008670) or Ehrlichia and Anaplasma Species by PCR (2007862).




Semi-Quantitative Indirect Fluorescent Antibody


Tue, Fri


1-5 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Serum Separator Tube (SST).

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

Test Number
Reference Interval
  A. Phagocytophilum Antibody, IgG Less than 1:80
  A. Phagocytophilum Antibody, IgM Less than 1:16

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Component Interpretation
Anaplasma phagocytophilum (HGA) Antibody, IgG Less than 1:80 - No significant level of IgG antibodies to A. phagocytophilum detected.
Greater than or equal to 1:80 - Suggestive of a recent or past infection with A. phagocytophilum
phagocytophilum (HGA) Antibody, IgM Less than 1:16 - No significant level of IgM antibodies to A. phagocytophilum detected.
Greater than or equal to 1:16 - Suggestive of a current or recent infection with A. phagocytophilum.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

86666 x2


Component Test Code* Component Chart Name LOINC
0097317 A. Phagocytophilum Antibody, IgG 23877-4
0097318 A. Phagocytophilum Antibody, IgM 23878-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • A. phagocytophilum IgG, IgM
  • Anaplasma phagocytophilum
Anaplasma phagocytophilum (HGA) Antibodies, IgG and IgM