Ordering Recommendation

Acceptable test for acute or convalescent phase of infection from Anaplasma phagocytophilium. May be useful when PCR testing is not an option (eg, outside the 2 week window for acute phase). However, PCR testing is generally preferred; refer to Tick-Borne Disease Panel by PCR, Blood (2008670) or Ehrlichia and Anaplasma Species by PCR (2007862).


Semi-Quantitative Indirect Fluorescent Antibody


Tue, Fri


1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Serum Separator Tube (SST).

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature


Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval
Test Number
Reference Interval
0097317 Anaplasma phagocytophilum (HGA) Antibody, IgG Less than 1:80 - No significant level of IgG antibodies to A. phagocytophilum detected.
Greater than or equal to 1:80 - Suggestive of a recent or past infection with A. phagocytophilum
0097318 Anaplasma phagocytophilum (HGA) Antibody, IgM Less than 1:16 - No significant level of IgM antibodies to A. phagocytophilum detected.
Greater than or equal to 1:16 - Suggestive of a current or recent infection with A. phagocytophilum.

Interpretive Data

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Hotline History
CPT Codes

86666 x2

Component Test Code* Component Chart Name LOINC
0097317 A. Phagocytophilum Antibody, IgG 23877-4
0097318 A. Phagocytophilum Antibody, IgM 23878-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
  • A. phagocytophilum IgG, IgM
  • Anaplasma phagocytophilum
Anaplasma phagocytophilum (HGA) Antibodies, IgG and IgM