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Cystatin C, Serum with Reflex to Estimated Glomerular Filtration Rate (eGFR)
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Ordering Recommendation
Calculate glomerular filtration rate in patients for whom serum creatinine may be misleading, such as the very obese, elderly, or malnourished patients.
Mnemonic
Methodology
Quantitative Nephelometry
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST), Plasma Separator Tube (PST), or Green (Lithium or Sodium Heparin).
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.4 mL)
Refrigerated.
Grossly hemolyzed specimens.
After separation from cells: Ambient: Unacceptable; Refrigerated: 1 week; Frozen: 3 months
Reference Interval
| Test Number |
Components |
Reference Interval |
|---|---|---|
| Cystatin C | 0.5 - 1.2 mg/L |
Interpretive Data
eGFR by Cystatin C Calculation not reported for Age 17 years or less
| eGFR Range (mL/min/BSA) |
Interpretive Data |
|---|---|
| 90 or greater | Stage 1: Normal or increased eGFR |
| 60-89 | Stage 2: Mildly decreased eGFR |
| 30-59 | Stage 3: Moderately descreased eGFR |
| 15-29 | Stage 4: Severely decreased eGFR |
| Less than 15 | Stage 5: Kidney Failure |
FDA
Note
If the patient's age and/or gender is unknown or is 18 years or younger, then Cystatin C Reflex will not be ordered. If age is greater than 18, Cystatin C reflex will be added at no additional charge.
Hotline History
CPT Codes
82610
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0095228 | Cystatin C | 33863-2 |
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