Optimize drug therapy and monitor patient adherence.
Quantitative High Performance Liquid Chromatography
Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.
Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), green (sodium heparin), gray (sodium fluoride/potassium oxalate). Avoid use of separator tubes and gels.
Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
After separation from cells: Ambient: 48 hours; Refrigerated: 1 month; Frozen: 6 months
Effective August 19, 2019
|Therapeutic Range||30-60 µg/mL|
|Toxic Level||Greater than 120 µg/mL|
Patient pharmacokinetics may be variable due to age, co-medications, and/or compromised renal function. Adverse effects may include nausea, vomiting, dizziness, blurred vision and ataxia. Felbamate use may increase the incidence of liver failure and aplastic anemia.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|