Estradiol (Adult Males, Children, Postmenopausal Females, or Individuals on Estrogen-Suppressing Hormone Therapy)
Use this mass spectrometry test to measure a wide range of estradiol concentrations. Most useful when low estradiol concentrations are expected, regardless of the patient’s sex assigned at birth. Use to monitor estradiol in individuals on estrogen-suppressing hormone therapies (eg, aromatase inhibitors or testosterone).
Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry
New York DOH Approval Status
Serum separator tube, lavender (EDTA), pink (K2EDTA) or green (sodium or lithium heparin).
Separate serum or plasma from cells within 2 hours after collection. Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min 0.3 mL) Indicate age and sex of patient on test request form AND specimen tube.
After separation from cells: Ambient: 48 hours; Refrigerated: 1 week; Frozen: 1 month
|Reference Intervals for Estradiol-Children
IV and V
less than 8.0 pg/mL
less than 10.0 pg/mL
less than 56.0 pg/mL
less than 7.0 pg/mL
less than 11.0 pg/mL
less than 36.0 pg/mL
|Reference Intervals for Estradiol-Adults
|Females 18 Years and Older
||Males 18 years and Older
Early Follicular: 30.0-100.0 pg/mL
Late Follicular: 100.0-400.0 pg/mL
Luteal: 50.0-150.0 pg/mL
|Postmenopausal: 2.0-21.0 pg/mL|
For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/0093247.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
|Component Test Code*||Component Chart Name||LOINC|
|0093247||Estradiol by Mass Spec||35384-7|
- Estradiol (E2)
- Ultrasensitive Estradiol