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Dengue Fever Virus Antibody, IgM
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Ordering Recommendation
May be used to diagnose dengue during acute phase of disease (>5 days after symptom onset). Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Wed, Fri
Reported
1-5 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimen plainly as "acute or convalescent."
Refrigerated.
Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies. Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection.
However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.
Interpretive Data
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
FDA
Note
Hotline History
CPT Codes
86790
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0093098 | Dengue Fever Virus Antibody, IgM | 23992-1 |
Aliases
- Dengue Fever IgM
- Dengue Fever Virus IgM antibody
- Flavivirus
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