Ordering Recommendation

Aids in detecting past dengue infection. Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."

Storage/Transport Temperature


Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)


Semi-Quantitative Enzyme-Linked Immunosorbent Assay


Mon, Wed, Fri


1-5 days

Reference Interval

1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection.

Interpretive Data

Patients in the early stage of dengue fever virus infection may not have detectable IgG antibodies, as the IgG response may take several weeks to develop.  In the absence of detectable IgG, testing for IgM class antibody is strongly recommended.  The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0093097 Dengue Fever Virus Antibody, IgG 23991-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Dengue Fever IgG
  • Dengue Fever Virus IgG antibody
  • Flavivirus
Dengue Fever Virus Antibody, IgG