Ordering Recommendation

May aid in the diagnosis of dengue when timing of infection is uncertain. Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Mnemonic
DENGUE AB
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon, Wed, Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0093097 Dengue Fever Virus Antibody, IgG 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection.
0093098 Dengue Fever Virus Antibody, IgM 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection.
However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data



Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

86790 x2

Components
Component Test Code* Component Chart Name LOINC
0093097 Dengue Fever Virus Antibody, IgG 23991-3
0093098 Dengue Fever Virus Antibody, IgM 23992-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Dengue Fever Ab Panel
  • Dengue Fever Antibodies
  • Dengue Fever IgG and IgM Antibodies
  • Flavivirus
Dengue Fever Virus Antibodies, IgG and IgM