Ordering Recommendation

May aid in the diagnosis of dengue when timing of infection is uncertain. Testing should also be considered for other arthropod-borne viruses with similar symptomology based on clinical presentation and travel history.

Mnemonic
DENGUE AB
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Mon, Wed, Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute or convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0093097 Dengue Fever Virus Antibody, IgG 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgG antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgG antibody to dengue fever virus detected, which may indicate a current or past infection.
0093098 Dengue Fever Virus Antibody, IgM 1.64 IV or less: Negative - No significant level of detectable dengue fever virus IgM antibody.
1.65-2.84 IV: Equivocal - Questionable presence of antibodies.  Repeat testing in 10-14 days may be helpful.
2.85 IV or greater: Positive - IgM antibody to dengue fever virus detected, which may indicate a current or recent infection.
However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note
Hotline History
N/A
CPT Codes

86790 x2

Components
Component Test Code* Component Chart Name LOINC
0093097 Dengue Fever Virus Antibody, IgG 23991-3
0093098 Dengue Fever Virus Antibody, IgM 23992-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Dengue Fever Ab Panel
  • Dengue Fever Antibodies
  • Dengue Fever IgG and IgM Antibodies
  • Flavivirus
Dengue Fever Virus Antibodies, IgG and IgM