Ordering Recommendation

Detect antibodies for P/Q type voltage-gated calcium channels. Aid in the evaluation of muscle weakness in the context neuromuscular junction disorder with or without cancer, or the diagnosis of paraneoplastic neurological syndromes.

Mnemonic
VGCC AB
Methodology

Quantitative Radioimmunoassay

Performed

Tue

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Plain Red or Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. CSF. Hemolyzed or grossly lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 72 hours; Refrigerated: 2 weeks; Frozen: 1 month

Reference Interval

Effective November 14, 2011

Negative 0.0 to 24.5 pmol/L
Indeterminate 24.6 to 45.6 pmol/L
Positive 45.7 pmol/L or greater

Interpretive Data



Compliance Category

Modified FDA

Note
Hotline History
N/A
CPT Codes

83519

Components
Component Test Code* Component Chart Name LOINC
0092629 P/Q-Type Calcium Channel Antibody 33980-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lambert Eaton
  • Lambert-Eaton
  • P/Q calcium channel
  • VGCC Ab
P/Q-Type Voltage-Gated Calcium Channel (VGCC) Antibody