Bile Acids, Fractionated and Total by LC-MS/MS

0092610
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Example Reports
Abnormal
Normal

Ordering Recommendation

Aids in the evaluation of liver function and intrahepatic cholestasis of pregnancy. Use to monitor patients on bile acid therapy. This assay is not useful for the diagnosis of inborn errors of bile acid metabolism.

Mnemonic

BILE ACIDS

Methodology

Quantitative High Performance Liquid Chromatography-Tandem Mass Spectrometry

Performed

Tue, Thu, Sat

Reported

1-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Patient should fast for a minimum of eight hours prior to specimen collection.

Collect

Plain red or serum separator tube.

Specimen Preparation

After clot formation, centrifuge specimen and pour off serum into a transport tube. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated. Store specimen refrigerated or frozen.

Unacceptable Conditions
Remarks
Stability

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 3 months

Reference Interval

7 years and older:
Cholic acid (CA) 0-1.9 µmol/L
Chenodeoxycholic acid (CDC) 0-3.4 µmol/L
Deoxycholic acid (DCA) 0-2.5 µmol/L
Ursodeoxycholic acid (UDC) 0-1.0 µmol/L
Total 0-7.0 µmol/L

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Reference intervals were derived using samples obtained after an overnight fast.

Hotline History

N/A

CPT Codes

83789

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Components

Component Test Code* Component Chart Name LOINC
0092611 Bile Acids - Cholic Acid 30518-5
0092612 Bile Acids - Deoxycholic Acid 30520-1
0092613 Bile Acids - Chenodeoxycholic Acid 30519-3
0092614 Total Bile Acids 14628-2
0093240 Bile Acids - Ursodeoxycholic Acid 55159-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Bile Salts
  • Chenodeoxycholic Acid
  • Cholic Acid
  • Deoxycholic Acid
  • Fractionated Bile Acids
  • Ursodeoxycholic Acid (UDC)
Bile Acids, Fractionated and Total by LC-MS/MS